AIMC Topic: Esophageal Squamous Cell Carcinoma

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Real-time automated diagnosis of precancerous lesions and early esophageal squamous cell carcinoma using a deep learning model (with videos).

Gastrointestinal endoscopy Aug 21, 2019
BACKGROUND AND AIMS: We developed a system for computer-assisted diagnosis (CAD) for real-time automated diagnosis of precancerous lesions and early esophageal squamous cell carcinomas (ESCCs) to assist the diagnosis of esophageal cancer.
Adolescent Esophageal Neoplasms Humans Precancerous Conditions Retrospective Studies Esophageal Squamous Cell Carcinoma Female Narrow Band Imaging Aged Male Young Adult Middle Aged Adult Diagnosis, Computer-Assisted Sensitivity and Specificity Deep Learning
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Using a deep learning system in endoscopy for screening of early esophageal squamous cell carcinoma (with video).

Gastrointestinal endoscopy Jul 11, 2019
BACKGROUND AND AIMS: Few artificial intelligence-based technologies have been developed to improve the efficiency of screening for esophageal squamous cell carcinoma (ESCC). Here, we developed and validated a novel system of computer-aided detection ...
Humans Female Reproducibility of Results Aged Image Interpretation, Computer-Assisted Pattern Recognition, Automated Esophageal Squamous Cell Carcinoma Deep Learning Young Adult ROC Curve Adult Predictive Value of Tests Male Area Under Curve Middle Aged Endoscopy, Gastrointestinal
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Classification for invasion depth of esophageal squamous cell carcinoma using a deep neural network compared with experienced endoscopists.

Gastrointestinal endoscopy May 8, 2019
BACKGROUND AND AIMS: Cancer invasion depth is a critical factor affecting the choice of treatment in patients with superficial squamous cell carcinoma (SCC). However, the diagnosis of invasion depth is currently subjective and liable to interobserver...
Aged Aged, 80 and over Adult Male Middle Aged Humans Neural Networks, Computer Female Gastroenterologists Deep Learning Neoplasm Invasiveness Esophageal Neoplasms Esophageal Squamous Cell Carcinoma Esophagoscopy
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Identification of esophageal cancer pathway deviation and construction of a diagnosis model using three kernel genes.

Journal of cellular physiology Mar 5, 2019
The purpose of this study is to better understand the role of interleukin 35 (IL35) in esophageal carcinoma by comparing the mRNA level in Barrett's esophageal mucosa and in matched normal squamous mucosa and to understand how the diagnosis model wor...
Interleukin-12 Subunit p35 Gene Expression Regulation, Neoplastic Models, Genetic Databases, Genetic Early Detection of Cancer Nerve Tissue Proteins Predictive Value of Tests Esophageal Neoplasms Cyclic AMP Response Element-Binding Protein Esophageal Squamous Cell Carcinoma Hepatocyte Nuclear Factor 1-beta Biomarkers, Tumor Gene Expression Profiling Transcriptome Case-Control Studies Deep Learning Humans Reproducibility of Results
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Artificial intelligence for the real-time classification of intrapapillary capillary loop patterns in the endoscopic diagnosis of early oesophageal squamous cell carcinoma: A proof-of-concept study.

United European gastroenterology journal Jan 6, 2019
BACKGROUND: Intrapapillary capillary loops (IPCLs) represent an endoscopically visible feature of early squamous cell neoplasia (ESCN) which correlate with invasion depth - an important factor in the success of curative endoscopic therapy. IPCLs visu...
Esophageal Squamous Cell Carcinoma Esophagoscopy Humans Male Artificial Intelligence Image Processing, Computer-Assisted Female Early Detection of Cancer Reproducibility of Results Taiwan Sensitivity and Specificity Neovascularization, Pathologic
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Grape Seed Proanthocyanidin Extract Inhibits Human Esophageal Squamous Cancerous Cell Line ECA109 via the NF-B Signaling Pathway.

Mediators of inflammation Dec 17, 2018
Esophageal squamous cell carcinoma is the most common type of squamous cell carcinoma. Grape seed proanthocyanidin extract (GSPE) is considered to exhibit anticancer activity against several different types of cancer. We aimed to determine whether GS...
NF-kappa B Signal Transduction Humans Esophageal Neoplasms Cell Movement Proanthocyanidins Cell Line, Tumor Apoptosis Enzyme-Linked Immunosorbent Assay Esophageal Squamous Cell Carcinoma Cell Survival Cell Proliferation Caspase 3 Grape Seed Extract
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Diagnosis using deep-learning artificial intelligence based on the endocytoscopic observation of the esophagus.

Esophagus : official journal of the Japan Esophageal Society Dec 13, 2018
BACKGROUND AND AIMS: The endocytoscopic system (ECS) helps in virtual realization of histology and can aid in confirming histological diagnosis in vivo. We propose replacing biopsy-based histology for esophageal squamous cell carcinoma (ESCC) by usin...
Humans Algorithms Retrospective Studies Esophageal Neoplasms Sensitivity and Specificity Gastroesophageal Reflux Deep Learning Esophageal Squamous Cell Carcinoma ROC Curve Esophagitis Esophagoscopy
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Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC).

Clinical epigenetics Dec 15, 2017
BACKGROUND: DNA methylation has been implicated as a promising biomarker for precise cancer diagnosis. However, limited DNA methylation-based biomarkers have been described in esophageal squamous cell carcinoma (ESCC).
Serine-Threonine Kinase 3 Middle Aged Logistic Models CpG Islands Humans Epigenesis, Genetic Promoter Regions, Genetic Machine Learning Databases, Genetic Esophageal Squamous Cell Carcinoma Female Sequence Analysis, DNA Pseudogenes Carcinoma, Squamous Cell Repressor Proteins Aged DNA Methylation Sensitivity and Specificity Early Detection of Cancer Biomarkers, Tumor Protein Serine-Threonine Kinases Male DNA-Binding Proteins Esophageal Neoplasms
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Serum levels of chemical elements in esophageal squamous cell carcinoma in Anyang, China: a case-control study based on machine learning methods.

BMJ open Sep 24, 2017
OBJECTIVES: Esophageal squamous cell carcinoma (ESCC) is the predominant form of esophageal carcinoma with extremely aggressive nature and low survival rate. The risk factors for ESCC in the high-incidence areas of China remain unclear. We used machi...
Male Middle Aged Case-Control Studies Selenium Zinc Copper Esophageal Neoplasms Esophageal Squamous Cell Carcinoma Female Carcinoma, Squamous Cell Reproducibility of Results Risk Factors Biomarkers, Tumor Humans Machine Learning Retrospective Studies
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Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma Raman spectroscopy and a deep learning algorithm.

World journal of gastroenterology Apr 14, 2025
BACKGROUND: Esophageal squamous cell carcinoma is a major histological subtype of esophageal cancer. Many molecular genetic changes are associated with its occurrence. Raman spectroscopy has become a new method for the early diagnosis of tumors becau...
Early Detection of Cancer Esophagus Neoplasm Grading Esophageal Neoplasms Esophageal Squamous Cell Carcinoma Humans Algorithms Male Deep Learning Spectrum Analysis, Raman
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