AIMC Topic: Fatty Acids

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BLVRA promotes glioblastoma progression by regulating fatty acid metabolism.

Scientific reports
Fatty acid metabolism is critically involved in glioblastoma (GBM) pathogenesis; however, its regulatory mechanisms remain incompletely understood. In this study, we identified biliverdin reductase A (BLVRA) as a novel metabolic driver and prognostic...

FAC-Z analysis of edible oils: The application of electrochemical impedance (Z) spectroscopy for supervised machine learning-based prediction of fatty acid composition (FAC) in edible oils.

Food chemistry
The primary fatty acid makeup of a comprehensive set of edible oils was ascertained using an electrochemical impedance spectroscopic approach. The electrical signatures of edible oils (i.e impedance spectra) were recorded and a neural network was use...

Phenolic Profile as a Powerful Machine Learning Tool for Identification, Traceability, and Quality Control of Olive Cultivars.

Journal of agricultural and food chemistry
This study investigates the phenolic and fatty acid profiles of olives from four cultivars (Arbequina, Arbosana, Frantene, and Koroneiki), widely grown in the Mediterranean region and collected at different ripening stages in Italy. The aim was to a...

Long chain fatty acid transport via SLC27A1 enhances DAG-3-P synthesis and accelerates colorectal cancer metastasis.

Scientific reports
Colorectal cancer (CRC) is a major global health issue. Despite advancements in treatment, CRC patients still face challenges of metastasis and variable prognosis. Circulating tumor cells (CTCs) shed from the primary tumor into the peripheral blood c...

Development of data driven models to accurately estimate density of fatty acid ethyl esters.

Scientific reports
Fatty acid ethyl esters (FAEEs) are widely used in biofuels, pharmaceuticals, and lubricants, offering an eco-friendly alternative due to their biodegradability and renewable nature, contributing to environmental sustainability. The objective of this...

Computationally unmasking each fatty acyl C=C position in complex lipids by routine LC-MS/MS lipidomics.

Nature communications
Identifying carbon-carbon double bond (C=C) positions in complex lipids is essential for elucidating physiological and pathological processes. Currently, this is impossible in high-throughput analyses of native lipids without specialized instrumentat...

Predicting the composition of multiple soybean varieties from whole and ground seeds using Fourier transform near-infrared spectroscopy (FT-NIRS) and machine learning.

Food chemistry
Soybean is being increasingly included in human diets, highlighting the importance of determining its composition. Although Fourier-Transform Near-Infrared Spectroscopy (FT-NIRS) has become a promising technology, currently used models remain limited...

SPP1 promotes malignant characteristics and drug resistance in hepatocellular carcinoma by activating fatty acid metabolic pathway.

Functional & integrative genomics
Hepatocellular carcinoma (HCC) progression and prognosis are influenced by various molecular markers. This study aimed to identify the hub gene associated with HCC clinical characteristics and its role in HCC progression. Differentially expressed gen...

Effect of fatty acid composition on rosemary antioxidants in stabilizing woody edible oils: a kinetic and machine learning analysis of volatiles under accelerated oxidation.

Food chemistry
Prioritizing woody oil-bearing crops is essential to addressing edible oil supply-demand imbalances, yet oxidation remains a key challenge. Rosemary crude extract (RCE), an approved food-grade antioxidant, requires further evaluation for stabilizing ...

Impact of dairy intake on circulating fatty acids and associations with blood pressure: A randomized crossover trial.

Nutrition, metabolism, and cardiovascular diseases : NMCD
BACKGROUND AND AIMS: This study aimed to investigate the effects of high and adequate dairy intake (>4, 2-3 serving/day, respectively) on circulating fatty acids (FAs) and their associations with blood pressure (BP).