BACKGROUND: Static carcinoembryonic antigen (CEA) levels are well‑established prognostic markers in patients with gastric cancer, but the significance of their dynamic trajectories over time has rarely been reported.
BACKGROUND: Craniofacial phenotyping is essential for individualized orthodontic diagnosis and treatment planning. Traditional skeletal classifications, such as the ANB angle, may oversimplify complex relationships among malocclusion types. Machine l...
BACKGROUND: Organoids have attracted enormous interest in disease modeling, drug screening, and precision medicine. However, developing robust patient-derived organoids (PDOs) was time-consuming, costly, and had low success rates for certain cancer t...
Journal of pharmaceutical and biomedical analysis
Jul 25, 2025
Primary Sjögren's Syndrome (pSS) is a complex autoimmune disease with an unclear etiology. Due to the lack of a single diagnostic gold standard, multidisciplinary and invasive examinations are often required for pSS, underscoring the urgent need for ...
OBJECTIVE: To explore the influence related factors of endoscopic assistant in gasless transaxillary endoscopic thyroidectomy by using machine learning and nomogram, and construct an endoscopic assistant system.
BACKGROUND: Extrinsic adenomyosis exhibits heterogeneous clinical symptoms, with pain being more commonly reported. The relationship between magnetic resonance imaging (MRI) feature and symptom remains unclear.
Consumer-driven blueberry quality improvement requires a deeper understanding of how metabolic composition influences sensory perception. This study integrates untargeted metabolomics and machine learning to identify biomarker metabolites shaping sen...
BACKGROUND: Immune checkpoint inhibitors (ICIs) are essential first-line treatments for recurrent or metastatic non-small cell lung cancer (NSCLC). However, predicting their effectiveness and the occurrence of immunotherapy-related adverse events (ir...
Hyperspectral imaging (HSI) holds significant potential for transforming the field of computational pathology. However, the number of HSI-based research studies remains limited, and in many cases, the advantages of HSI over traditional RGB imaging ha...
We evaluated whether predicted continuous disease representations could enhance genetic discovery beyond case-control genome-wide association study (GWAS) phenotypes across eight complex diseases in up to 485,448 UK Biobank participants. Predicted ph...
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