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Computed tomography-derived quantitative imaging biomarkers enable the prediction of disease manifestations and survival in patients with systemic sclerosis.

RMD open
INTRODUCTION: Systemic sclerosis (SSc) is a complex inflammatory vasculopathy with diverse symptoms and variable disease progression. Despite its known impact on body composition (BC), clinical decision-making has yet to incorporate these biomarkers....

Impact of mHealth on Postoperative Quality of Life, Self-Management, and Dysfunction in Patients With Oral and Maxillofacial Tumors: Nonrandomized Controlled Trial.

JMIR mHealth and uHealth
BACKGROUND: With a focus on postoperative dysfunctions that may occur after maxillofacial tumor resection and the difficulties faced during home rehabilitation, we developed a mobile health app based on nurse-patient cooperation. The app extends reha...

Suicide Risk Screening in Jails: Protocol for a Pilot Study Leveraging the Mental Health Research Network Algorithm and Health Care Data.

JMIR research protocols
BACKGROUND: Suicide in local jails occurs at a higher rate than in the general population, requiring improvements to risk screening methods. Current suicide risk screening practices in jails are insufficient: They are commonly not conducted using val...

Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective Analysis.

Journal of medical Internet research
BACKGROUND: Colorectal cancer (CRC) screening rates remain disproportionately low among Hispanic and Latino populations compared to non-Hispanic White populations. While artificial intelligence (AI) shows promise in health care delivery, concerns exi...

Regional free-water diffusion is more strongly related to neuroinflammation than neurodegeneration.

Journal of neurology
INTRODUCTION: Recent research has suggested that neuroinflammation may be important in the pathogenesis of neurodegenerative diseases. Free-water diffusion (FWD) has been proposed as a non-invasive neuroimaging-based biomarker for neuroinflammation.

Comprehensive analysis and experimental validation of BST1 as a novel diagnostic biomarker for pediatric sepsis using multiple machine learning algorithms.

European journal of pediatrics
Bone marrow stromal cell antigen-1 (BST1) expression is elevated in a variety of human diseases, but its relationship with pediatric sepsis is unclear. This study aimed to investigate the expression of BST1 in pediatric sepsis patients and its value ...

Accurate Tracking of Locomotory Kinematics in Mice Moving Freely in Three-Dimensional Environments.

eNeuro
Marker-based motion capture (MBMC) is a powerful tool for precise, high-speed, three-dimensional tracking of animal movements, enabling detailed study of behaviors ranging from subtle limb trajectories to broad spatial exploration. Despite its proven...

Fully automated workflow for designing patient-specific orthopaedic implants: Application to total knee arthroplasty.

PloS one
Background Osteoarthritis affects about 528 million people worldwide, causing pain and stiffness in the joints. Arthroplasty is commonly performed to treat joint osteoarthritis, reducing pain and improving mobility. Nevertheless, a significant share ...

Personalized machine learning models for noninvasive hypoglycemia detection in people with type 1 diabetes using a smartwatch: Insights into feature importance during waking and sleeping times.

PloS one
Hypoglycemia is a major challenge for people with diabetes. Therefore, glycemic monitoring is an important aspect of diabetes management. However, current methods such as finger pricking and continuous glucose monitoring systems (CGMS) are invasive, ...

Statistical and machine learning models for predicting university dropout and scholarship impact.

PloS one
Although student dropout is an inevitable aspect of university enrollment, when analyzed, universities can gather information which enables them to take preventative actions that mitigate dropout risk. We study a data set consisting of 4,424 records ...