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A Deep Learning-Enabled Workflow to Estimate Real-World Progression-Free Survival in Patients With Metastatic Breast Cancer: Study Using Deidentified Electronic Health Records.

JMIR cancer
BACKGROUND: Progression-free survival (PFS) is a crucial endpoint in cancer drug research. Clinician-confirmed cancer progression, namely real-world PFS (rwPFS) in unstructured text (ie, clinical notes), serves as a reasonable surrogate for real-worl...

fNIRS experimental study on the impact of AI-synthesized familiar voices on brain neural responses.

Scientific reports
With the advancement of artificial intelligence (AI) speech synthesis technology, its application in personalized voice services and its potential role in emotional comfort have become research focal points. This study aims to explore the impact of A...

Machine learning approach for differentiating iron deficiency anemia and thalassemia using random forest and gradient boosting algorithms.

Scientific reports
Formulas based on red blood cell indices have been used to differentiate between iron deficiency anemia (IDA) and thalassemia (Thal). However, they exhibit varying efficiencies. In this study, we aimed to develop a tool for discriminating between IDA...

Machine learning for grading prediction and survival analysis in high grade glioma.

Scientific reports
We developed and validated a magnetic resonance imaging (MRI)-based radiomics model for the classification of high-grade glioma (HGG) and determined the optimal machine learning (ML) approach. This retrospective analysis included 184 patients (59 gra...

COMPASS: Computational mapping of patient-therapist alliance strategies with language modeling.

Translational psychiatry
The therapeutic working alliance is a critical predictor of psychotherapy success. Traditionally, working alliance assessment relies on questionnaires completed by both therapists and patients. In this paper, we present COMPASS, a novel framework to ...

Evaluation of a Machine Learning Model Based on Laboratory Parameters for the Prediction of Influenza A and B in Chongqing, China: Multicenter Model Development and Validation Study.

Journal of medical Internet research
BACKGROUND: Influenza viruses are major pathogens responsible for acute respiratory infections in humans, which present with symptoms such as fever, cough, sore throat, muscle pain, and fatigue. While molecular diagnostics remain the gold standard, t...

Challenges in Implementing Artificial Intelligence in Breast Cancer Screening Programs: Systematic Review and Framework for Safe Adoption.

Journal of medical Internet research
BACKGROUND: Artificial intelligence (AI) studies show promise in enhancing accuracy and efficiency in mammographic screening programs worldwide. However, its integration into clinical workflows faces several challenges, including unintended errors, t...

Patients' Perceptions of Artificial Intelligence Acceptance, Challenges, and Use in Medical Care: Qualitative Study.

Journal of medical Internet research
BACKGROUND: Artificial intelligence (AI) is increasingly used in medical care, particularly in the areas of image recognition and processing. While its practical use in other areas is still limited, an understanding of patients' needs is essential fo...

Extracting Multifaceted Characteristics of Patients With Chronic Disease Comorbidity: Framework Development Using Large Language Models.

JMIR medical informatics
BACKGROUND: Research on chronic multimorbidity has increasingly become a focal point with the aging of the population. Many studies in this area require detailed patient characteristic information. However, the current methods for extracting such inf...

Deep Learning-Based Chronic Obstructive Pulmonary Disease Exacerbation Prediction Using Flow-Volume and Volume-Time Curve Imaging: Retrospective Cohort Study.

Journal of medical Internet research
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common and progressive respiratory condition characterized by persistent airflow limitation and symptoms such as dyspnea, cough, and sputum production. Acute exacerbations (AE) of COPD (AE...