AIMC Topic: Gels

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Generation of Interconnected Neural Clusters in Multiscale Scaffolds from Human-Induced Pluripotent Stem Cells.

ACS applied materials & interfaces
The development of in vitro neural networks depends to a large extent on the scaffold properties, including the scaffold stiffness, porosity, and dimensionality. Herein, we developed a method to generate interconnected neural clusters in a multiscale...

Alginate fiber toughened gels similar to skin intelligence as ionic sensors.

Carbohydrate polymers
The stretchable hydrogels provide potential alternatives to bionic skins. However, skin simulation remains seriously challenging due to its complex nature, including mechanical property, protective effect, and sensory capability. Herein, conductive g...

Nanoemulsions and acidified milk gels as a strategy for improving stability and antioxidant activity of yarrow phenolic compounds after gastrointestinal digestion.

Food research international (Ottawa, Ont.)
The aim of this study was to improve the stability and antioxidant activity of yarrow phenolic compounds upon an in vitro simulated gastrointestinal digestion. Therefore, two types of caseins-based delivery systems, sodium caseinate stabilized nanoem...

Use of Topical Lidocaine Gel Plus Paracervical Blockade vs. Paracervical Blockade Alone for Pain Management During Manual Vacuum Aspiration: ADouble-Blind, Randomized, Placebo-Controlled Trial.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
OBJECTIVE: To evaluate if the use of lidocaine gel applied to the cervix prior to manual vacuum aspiration (MVA) in addition to paracervical blockade is useful in reducing the level of pain associated with the procedure.

A novel method for the production of core-shell microparticles by inverse gelation optimized with artificial intelligent tools.

International journal of pharmaceutics
Numerous studies have been focused on hydrophobic compounds encapsulation as oils. In fact, oils can provide numerous health benefits as synergic ingredient combined with other hydrophobic active ingredients. However, stable microparticles for pharma...

Modeling of glucose release from native and modified wheat starch gels during in vitro gastrointestinal digestion using artificial intelligence methods.

International journal of biological macromolecules
Estimation of the amounts of glucose release (AGR) during gastrointestinal digestion can be useful to identify food of potential use in the diet of individuals with diabetes. In this work, adaptive neuro-fuzzy inference system (ANFIS), genetic algori...

Hydrophilic Ionic Liquids as Ingredients of Gel-Based Dermal Formulations.

AAPS PharmSciTech
Ionic liquids (ILs) have several properties that offer many advantages in dermal drug delivery systems. Depending on the chemical structure, ILs can be used for protection against microorganisms, to enhance skin penetration, and as a solvent. In the ...

The Application of Anisotropically Collapsing Gels, Deep Learning, and Optical Microscopy for Chemical Characterization of Nanoparticles and Nanoplastics.

Langmuir : the ACS journal of surfaces and colloids
The surface chemistry of nanomaterials, particularly the density of functional groups, governs their behavior in applications such as bioanalysis, bioimaging, and environmental impact studies. Here, we report a precise method to quantify carboxyl gro...

Machine learning predictions of drug release from isocyanate-derived aerogels.

Journal of materials chemistry. B
This work utilized machine learning (ML) algorithms to predict and validate the drug release kinetics of a short worm-like nanostructured isocyanate-derived aerogel: the first time ML has been employed to study the drug delivery properties of this i...

Dual-responsive biohybrid neutrobots for active target delivery.

Science robotics
Swimming biohybrid microsized robots (e.g., bacteria- or sperm-driven microrobots) with self-propelling and navigating capabilities have become an exciting field of research, thanks to their controllable locomotion in hard-to-reach areas of the body ...