FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Dec 15, 2025
Intracerebral hemorrhage (ICH) is a major cause of death and disability worldwide. Despite treatment advances, reliable prognostic biomarkers are still lacking. While phagocytosis regulation is implicated in ICH pathogenesis, its potential for diagno...
UNLABELLED: Precision oncology is becoming increasingly integral to clinical practice, demonstrating notable improvements in treatment outcomes. Whereas molecular data provide comprehensive insights, obtaining such data remains costly and time-consum...
This study aimed to comprehensively investigate the regulatory mechanism and clinical value of secreted phosphoprotein 1 (SPP1) in the three-stage progression of "smoking-chronic obstructive pulmonary disease (COPD)-carcinogenesis" in lung squamous ...
OBJECTIVE: Diagnosis of hepatocellular carcinoma (HCC) remains challenging for clinicians. Machine learning approaches and big data analyses are viable strategies for identifying HCC diagnostic markers.
Diagnosing Alzheimer's disease based on gene expression data extracted from microarrays is still an open field of research. Due to the availability of whole-genome data through microarrays technology, diagnosis accuracy is expected to be improved. De...
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease often leading to rapidly progressive glomerulonephritis. Oxidative stress plays a critical role in the development and progression of ANCA-associ...
BACKGROUND: Juvenile idiopathic arthritis (JIA), superseding juvenile rheumatoid arthritis (JRA), is a chronic autoimmune disease affecting children and characterized by various types of childhood arthritis. JIA manifests clinically with joint inflam...
Atherosclerosis (AS) is a systemic disease closely related to inflammatory cell infiltration and immune cell activation, often leading to myocardial infarction and stroke and is the leading cause of death worldwide. AS is asymptomatic in its early st...
Age-related hearing loss (HL) and sarcopenia (ARS) are prevalent geriatric syndromes sharing common risk factors. This study aimed to identify shared biomarkers and elucidate convergent pathogenic mechanisms. Transcriptomic datasets were obtained fro...
Acute kidney injury (AKI) is a serious condition characterized by a rapid decline in renal function, leading to severe complications. Recent findings suggest that cuproptosis-related genes (CuRGs) influence AKI mechanisms. This study investigated CuR...
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