AIMC Topic: Glucose

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Adaptations to excess choline in insulin resistant and Pcyt2 deficient skeletal muscle.

Biochemistry and cell biology = Biochimie et biologie cellulaire Sep 6, 2016
It was hypothesized that choline supplementation in insulin resistant (IR) CTP:phosphoethanolamine cytidylyltransferase deficient (Pcyt2) mice would ameliorate muscle function by remodeling glucose and fatty acid (FA) metabolism. Pcyt2 mice either re...
Adaptation, Physiological Fatty Acids Signal Transduction Administration, Oral Muscle, Skeletal Carnitine O-Palmitoyltransferase Choline Mice, Knockout Diacylglycerol O-Acyltransferase Gene Expression Regulation Animals Glucose Insulin Receptor Substrate Proteins PPAR alpha Mice Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Triglycerides Organic Cation Transport Proteins Stearoyl-CoA Desaturase Insulin Resistance RNA Nucleotidyltransferases Microtubule-Associated Proteins Lipogenesis Sterol Regulatory Element Binding Protein 1 fas Receptor
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Low osteocalcin level is a risk factor for impaired glucose metabolism in a Chinese male population.

Journal of diabetes investigation Dec 16, 2015
AIMS/INTRODUCTION: This study was to assess the association between serum osteocalcin level and glucose metabolism in a Chinese male population.
Glucose Metabolism Disorders Glucose Osteocalcin Asian People Glucose Tolerance Test Male Middle Aged China Humans Risk Factors Adult Cross-Sectional Studies
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Simultaneous determination of glucose, fructose, sucrose and sorbitol in the leaf and fruit peel of different apple cultivars by the HPLC-RI optimized method.

Food chemistry Dec 12, 2015
A high performance liquid chromatography method with refractive index detection (HPLC-RI), for simultaneous determination of glucose, fructose, sucrose and sorbitol in leaf and/or apple peel samples from nine apple (Malus domestica Borkh.) cultivars ...
Sorbitol Plant Leaves Glucose Chromatography, High Pressure Liquid Fruit Sucrose Fructose Food Additives Malus
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Cognitively impaired elderly exhibit insulin resistance and no memory improvement with infused insulin.

Neurobiology of aging Dec 1, 2015
Insulin resistance is a risk factor for Alzheimer's disease (AD), although its role in AD etiology is unclear. We assessed insulin resistance using fasting and insulin-stimulated measures in 51 elderly subjects with no dementia (ND; n = 37) and with ...
Humans Female Risk Factors Aged Blood-Brain Barrier Male Glucose Alzheimer Disease Insulin Cognition Disorders Cohort Studies Memory, Episodic Insulin Resistance
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HEPNet: A Knowledge Base Model of Human Energy Pool Network for Predicting the Energy Availability Status of an Individual.

PloS one Jun 8, 2015
HEPNet is an electronic representation of metabolic reactions occurring within human cellular organization focusing on inflow and outflow of the energy currency ATP, GTP and other energy associated moieties. The backbone of HEPNet consists of primary...
Ketoglutaric Acids Phosphocreatine Adenosine Triphosphate Energy Metabolism Semantics Uremia NAD Acyl Coenzyme A Carnitine Reproducibility of Results Glucose Models, Biological Knowledge Bases Humans Computer Simulation
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Dynamic mode decomposition for analysis and prediction of metabolic oscillations from time-lapse imaging of cellular autofluorescence.

Scientific reports Jul 2, 2025
Oscillations are a common phenomenon in cell biology. They are based on non-linear coupling of biochemical reactions and can show rich dynamic behavior as found in, for example, glycolysis of yeast cells. Here, we show that dynamic mode decomposition...
Humans Saccharomyces cerevisiae Optical Imaging NAD Time-Lapse Imaging Machine Learning Algorithms Glycolysis Glucose
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MIP-based electrochemical sensor with machine learning for accurate ZIKV detection in protein- and glucose-rich urine.

Analytical biochemistry Jul 1, 2025
Nowadays, a multitude of biosensors are being developed worldwide. However, a significant challenge arises when these biosensors are tested in real sample environments, as many of them fail to perform as expected. This can lead to ambiguous results a...
Humans Glucose Molecularly Imprinted Polymers Molecular Imprinting Machine Learning Zika Virus Biosensing Techniques Electrochemical Techniques
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A stretchable, adhesive, and wearable hydrogel-based patches based on a bilayer PVA composite for online monitoring of sweat by artificial intelligence-assisted smartphones.

Talanta May 15, 2025
Real-time monitoring of sweat using wearable devices faces challenges such as limited adhesion, mechanical flexibility, and accurate detection. In this work, we present a stretchable, adhesive, bilayer hydrogel-based patch designed for continuous mon...
Artificial Intelligence Wearable Electronic Devices Smartphone Monitoring, Physiologic Humans Polyvinyl Alcohol Sweat Adhesives Glucose Hydrogen-Ion Concentration Hydrogels Glucose Oxidase
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Optoelectronic-Coupled-Driven Microrobot for Biological Cargo Transport in Conductive Isosmotic Glucose Solution.

ACS applied materials & interfaces May 14, 2025
Electric field-driven micro/nanorobots, as micro/nanodevices with autonomous motion capability, have emerged as promising candidates for targeted cargo delivery in biomedical applications due to their advantages of label-free operation, selectivity, ...
Ferric Compounds Solutions Electric Conductivity Robotics Gold Glucose
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Integrating Bioinformatics and Machine Learning to Identify Glucose Metabolism-Related Biomarkers with Diagnostic and Prognostic Value for Patients with Kidney Renal Clear Cell Carcinoma.

Archivos espanoles de urologia Apr 1, 2025
BACKGROUND: Glucose metabolism plays a critical role in the development and progression of kidney renal clear cell carcinoma (KIRC). This study aimed to identify glucose metabolism-related biomarkers (GRBs) and therapeutic targets for KIRC diagnosis ...
Humans Machine Learning Prognosis Biomarkers, Tumor Computational Biology Glucose Kidney Neoplasms Carcinoma, Renal Cell
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