AIMC Topic: Gray Matter

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Automated Whole-Brain Focal Cortical Dysplasia Detection Using MR Fingerprinting With Deep Learning.

Neurology
BACKGROUND AND OBJECTIVES: Focal cortical dysplasia (FCD) is a common pathology for pharmacoresistant focal epilepsy, yet detection of FCD on clinical MRI is challenging. Magnetic resonance fingerprinting (MRF) is a novel quantitative imaging techniq...

Gray Matter Differences in Adolescent Psychiatric Inpatients: A Machine Learning Study of Bipolar Disorder and Other Psychopathologies.

Brain and behavior
BACKGROUND: Bipolar disorder (BD) is among the psychiatric disorders most prone to misdiagnosis, with both false positives and false negatives resulting in treatment delay. We employed a whole-brain machine learning approach focusing on gray matter v...

Juvenile Myoclonic Epilepsy Imaging Endophenotypes and Relationship With Cognition and Resting-State EEG.

Human brain mapping
Structural neuroimaging studies of patients with Juvenile Myoclonic Epilepsy (JME) typically present two findings: 1-volume reduction of subcortical gray matter structures, and 2-abnormalities of cortical thickness. The general trend has been to obse...

Analysis of Two Neuroanatomical Subtypes of Parkinson's Disease and Their Motor Progression Based on Semi-Supervised Machine Learning.

CNS neuroscience & therapeutics
BACKGROUND: The high heterogeneity of Parkinson's disease (PD) hinders personalized interventions. Brain structure reflects damage and neuroplasticity and is one of the biological bases of symptomatology. Subtyping PD in the framework of brain struct...

Unmasking the Dark Triad: A Data Fusion Machine Learning Approach to Characterize the Neural Bases of Narcissistic, Machiavellian and Psychopathic Traits.

The European journal of neuroscience
The Dark Triad (DT), encompassing narcissism, Machiavellianism and psychopathy traits, poses significant societal challenges. Understanding the neural underpinnings of these traits is crucial for developing effective interventions and preventive stra...

A multimodal vision transformer for interpretable fusion of functional and structural neuroimaging data.

Human brain mapping
Multimodal neuroimaging is an emerging field that leverages multiple sources of information to diagnose specific brain disorders, especially when deep learning-based AI algorithms are applied. The successful combination of different brain imaging mod...

In vivo neuropil density from anatomical MRI and machine learning.

Cerebral cortex (New York, N.Y. : 1991)
Brain energy budgets specify metabolic costs emerging from underlying mechanisms of cellular and synaptic activities. While current bottom-up energy budgets use prototypical values of cellular density and synaptic density, predicting metabolism from ...

Dissecting unique and common variance across body and brain health indicators using age prediction.

Human brain mapping
Ageing is a heterogeneous multisystem process involving different rates of decline in physiological integrity across biological systems. The current study dissects the unique and common variance across body and brain health indicators and parses inte...

Voxel-based morphometry and a deep learning model for the diagnosis of early Alzheimer's disease based on cerebral gray matter changes.

Cerebral cortex (New York, N.Y. : 1991)
This study aimed to analyse cerebral grey matter changes in mild cognitive impairment (MCI) using voxel-based morphometry and to diagnose early Alzheimer's disease using deep learning methods based on convolutional neural networks (CNNs) evaluating t...