Clinical pharmacology in drug development
Dec 11, 2014
Absolute oral bioavailability of canagliflozin was assessed by simultaneous oral administration with intravenous [(14) C]-canagliflozin microdose infusion in nine healthy men. Pharmacokinetics of canagliflozin, [(14) C]-canagliflozin, and total radio...
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
Nov 20, 2025
PURPOSE: To evaluate the effect of model-based deep-learning reconstruction (DLR) compared with that of compressed sensing-sensitivity encoding (CS) on cine cardiac magnetic resonance (CMR).
PURPOSE: Chemical exchange saturation transfer (CEST) imaging is highly sensitive to patient motion, which can compromise the reliability of quantitative molecular analysis. This study aims to develop and validate a deep learning-based motion correct...
The size of an individual's tongue relative to the oral cavity is associated with articulation speed [Feng, Lu, Zheng, Chi, and Honda, in Proceedings of the 10th Biennial Asia Pacific Conference on Speech, Language, and Hearing (2017), pp. 17-19)] an...
The study aimed to compare the morphometric and morphologic analyses of the bone structures of temporomandibular joint and masticatory muscles on Cone beam computed tomography (CBCT) in 62 healthy subjects and 33 subjects with temporomandibular dysfu...
Purpose To assess the influence of deep learning (DL)-based image reconstruction on acquisition time, volumetric results, and image quality of cine sequences in cardiac MRI. Materials and Methods This prospective study (performed from January 2023 to...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2023
This paper proposes a multitask deformable residual neural network, for full spatial muscle fiber orientation (MFO) estimation from ultrasound (US) images. It is developed based on the state-of-the-art model of residual UNet (ResUNet), which combines...
A solution of spectroscopic inverse problems, implying determination of target parameters of the research object via analysis of spectra of various origins, is an overly complex task, especially in case of strong variability of the research object. O...
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Sep 1, 2021
OBJECTIVE: To explore the clinical feasibility of applying deep learning (DL) reconstruction algorithm in low-dose thin-slice liver CT examination of healthy volunteers by comparing the reconstruction algorithm based on DL, filtered back projection (...
PURPOSE: To describe imaging produced by machine learning-based segmentation of high-resolution optical coherence tomography imaging of the intermediate capillary plexus and deep capillary plexus, layers of vessels not imaged well by dye-based angiog...
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