AIMC Topic: Healthy Volunteers

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Robot-induced perturbations of human walking reveal a selective generation of motor adaptation.

Science robotics May 24, 2017
The processes underlying the generation of motor adaptation in response to mechanical perturbations during human walking have been subject to debate. We used a robotic system to apply mechanical perturbations to step length and step height over conse...
Robotics Postural Balance Walking Male Cohort Studies Gait Analysis Motor Skills Adaptation, Physiological Gait Healthy Volunteers Humans Female Adult Biomechanical Phenomena Young Adult
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[A machine learning model using gut microbiome data for predicting changes of trimethylamine-N-oxide in healthy volunteers after choline consumption].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University Mar 20, 2017
OBJECTIVE: To establish a machine learning model based on gut microbiota for predicting the level of trimethylamine N-oxide (TMAO) metabolism in vivo after choline intake to provide guidance of individualized precision diet and evidence for screening...
Algorithms Gastrointestinal Microbiome RNA, Ribosomal, 16S Humans Machine Learning Healthy Volunteers Choline Methylamines Oxides Eggs
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PHARMACOKINETICS AND BIOEQUIVALENCE STUDIES OF TWO NIMESULIDE 100 mg TABLETS: UNIT DOSE, RANDOMIZED-SEQUENCE, TWO-WAY CROSSOVER STUDY IN HEALTHY VOLUNTEERS OF PAKISTANI POPULATION.

Acta poloniae pharmaceutica Mar 1, 2017
Single centered crossover, two cycles volunteer study was performed on 12 healthy male volunteers. Both reference and test, immediate release nimesulide formulation was given in a randomized manner with a washout period of 15 days and 5 mL of blood s...
Cross-Over Studies Area Under Curve Healthy Volunteers Models, Biological Half-Life Tablets Metabolic Clearance Rate Male Pakistan Humans Sulfonamides Chromatography, High Pressure Liquid Therapeutic Equivalency Administration, Oral Anti-Inflammatory Agents, Non-Steroidal Young Adult
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[Safety and Tolerance of Healthy People to Injection of Astragalosides-a New Drug for Coronary Heart Disease].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition Sep 1, 2016
OBJECTIVES: To assess the safety and tolerance of healthy volunteers to as tragalosides injection (AGI), and to determine a safe dose range for phase II clinical trial.
Saponins Humans Coronary Disease Liver Triterpenes Drugs, Chinese Herbal Healthy Volunteers
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Principal component analysis can decrease neural networks performance for incipient falls detection: A preliminary study with hands and feet accelerations.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Aug 1, 2016
Fall-related accidents constitute a major problem for elderly people and a burden to the health-care national system. It is therefore important to design devices (e.g., accelerometers) and machine learning algorithms able to recognize incipient falls...
Humans Neural Networks, Computer Monitoring, Ambulatory Algorithms Machine Learning Healthy Volunteers Walking Accidental Falls Adult Acceleration Principal Component Analysis
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Automatic and continuous assessment of ERPs for mismatch negativity detection.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Aug 1, 2016
Accurate and fast detection of event related potential (ERP) components is an unresolved issue in neuroscience and critical health care. Mismatch negativity (MMN) is a component of the ERP to an odd stimulus in a sequence of identical stimuli which h...
Evoked Potentials Acoustic Stimulation Evoked Potentials, Auditory Humans Electroencephalography Healthy Volunteers Machine Learning
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The effect of Intravenous Immunoglobulin (IVIG) on \textit{ex vivo} activation of human leukocytes.

Human antibodies Jan 1, 2016
INTRODUCTION: Intravenous immunoglobulin (IVIG) has been widely used to treat various conditions, including inflammatory and autoimmune diseases. IVIG has been shown to have a direct influence on neutrophils, eosinophils and lymphocytes. However, man...
Tetradecanoylphorbol Acetate Primary Cell Culture Dose-Response Relationship, Immunologic Healthy Volunteers Immunoglobulins, Intravenous Tumor Necrosis Factor-alpha Lymphocyte Activation Luminescent Measurements Leukocytes Extracellular Traps Humans
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