AIMC Topic: HeLa Cells
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OrgaNet: A Robust Network for Subcellular Organelles Classification in Fluorescence Microscopy Images.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2020
Automatic identification of subcellular compartments of proteins in fluorescence microscopy images is an important task to quantitatively evaluate cellular processes. A common problem for the development of deep learning based classifiers is that the...
In vitro monitoring of photoinduced necrosis in HeLa cells using digital holographic microscopy and machine learning.
Journal of the Optical Society of America. A, Optics, image science, and vision
Feb 1, 2020
Digital holographic microscopy supplemented with the developed cell segmentation and machine learning and classification algorithms is implemented for quantitative description of the dynamics of cellular necrosis induced by photodynamic treatment in ...
Automated sample preparation with SP3 for low-input clinical proteomics.
Molecular systems biology
Jan 1, 2020
High-throughput and streamlined workflows are essential in clinical proteomics for standardized processing of samples from a variety of sources, including fresh-frozen tissue, FFPE tissue, or blood. To reach this goal, we have implemented single-pot ...
In vitro cytotoxic, antioxidant, antibacterial and antifungal activity of Saussurea heteromalla indigenous to Pakistan.
Pakistan journal of pharmaceutical sciences
Nov 1, 2019
Medicinal plants are proven to reveal vast promising potential providing novel drug candidates to combat health-related problems. The aim of current study is to discover new drug compounds with anti-anticancer, antioxidant, antibacterial and antifung...
Min3: Predict microRNA target gene using an improved binding-site representation method and support vector machine.
Journal of bioinformatics and computational biology
Oct 1, 2019
MicroRNAs are single-stranded noncoding RNAs known to down-regulate target genes at the protein or mRNA level. Computational prediction of targets is essential for elucidating the detailed functions of microRNA. However, prediction specificity and se...
Enhancing fluorescent protein photostability through robot-assisted photobleaching.
Integrative biology : quantitative biosciences from nano to macro
Jul 16, 2018
Improving fluorescent proteins through the use of directed evolution requires robust techniques for screening large libraries of genetic variants. Here we describe an effective and relatively low-cost system for screening libraries of fluorescent pro...
GPU-based deep convolutional neural network for tomographic phase microscopy with ℓ1 fitting and regularization.
Journal of biomedical optics
Jun 1, 2018
Tomographic phase microscopy (TPM) is a unique imaging modality to measure the three-dimensional refractive index distribution of transparent and semitransparent samples. However, the requirement of the dense sampling in a large range of incident ang...
Antigenotoxic and apoptotic activities of essential oil of Correa.
Indian journal of pharmacology
Jan 1, 2016
OBJECTIVE: To study antigenotoxic and apoptotic activities of hydrodistilled essential oil from the leaves of Correa.
Effects of TGF-β1 on the Proliferation and Apoptosis of Human Cervical Cancer Hela Cells In Vitro.
Cell biochemistry and biophysics
Dec 1, 2015
To investigate the effects of TGF-β1 on the proliferation and apoptosis of cervical cancer Hela cells in vitro. Human cervical cancer Hela cells were cultured in vitro and divided into the experimental and control groups. In the experimental groups, ...
LncRNA ontology: inferring lncRNA functions based on chromatin states and expression patterns.
Oncotarget
Nov 24, 2015
Accumulating evidences suggest that long non-coding RNAs (lncRNAs) perform important functions. Genome-wide chromatin-states area rich source of information about cellular state, yielding insights beyond what is typically obtained by transcriptome pr...
Algorithms
Cells, Cultured
Neoplasms
Gene Expression Profiling
Cell Line, Tumor
Gene Regulatory Networks
RNA, Messenger
Models, Genetic
K562 Cells
Humans
Histones
HeLa Cells
Transcription Initiation Site
Gene Ontology
Hep G2 Cells
Methylation
Chromatin
Cell Line
Promoter Regions, Genetic
RNA, Long Noncoding
Lysine
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