Journal of pharmaceutical and biomedical analysis
Jan 27, 2016
Peptides' retention time prediction is gaining increasing popularity in liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomics. This is a promising approach for improving successful proteome mapping, useful both in identification ...
Bioorganic & medicinal chemistry letters
Dec 24, 2015
In present work we have designed and synthesized total twelve novel 3-(3-(1H-indol-3-yl)-3-phenylpropanoyl)-4-hydroxy-2H-chromen-2-one derivatives 13(a-l) using Ho(3+) doped CoFe2O4 nanoparticles as catalyst and evaluated for their potential antileis...
The use of fluorescence microscopy has undergone a major revolution over the past twenty years, both with the development of dramatic new technologies and with the widespread adoption of image analysis and machine learning methods. Many open source s...
Angewandte Chemie (International ed. in English)
Nov 3, 2025
Single-cell mass spectrometry (MS) offers unprecedented sensitivity for profiling cellular proteomes, yet widespread adoption is hindered by the cost of advanced instrumentation. Here, we broaden access to single-cell proteomics by combining capillar...
International journal of biological macromolecules
Jun 1, 2025
The N6-methyladenosine(m6A) modification plays crucial regulatory roles in various biological processes including gene expression regulation, RNA stability, splicing, and translation. Accurate prediction of m6A modification sites is essential for und...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
The potential of calcium imaging in high-throughput drug screening experiments remains underutilized, primarily because of time-intensive manual identification of cells.To overcome these challenges, we propose to use deep learning enhanced watershed ...
Mechanical forces have increasingly been recognized as a key regulator in the fate of cellular development and functionality. Different mechanical transduction methods, such as substrate stiffness and magnetic bead vibration, have been experimented w...
CONTEXT: Traditionally, Hook. f. (Asteraceae) has been reported to be effective in cancer treatment which motivated the authors to explore the plant for novel anticancer compounds.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Nov 1, 2021
Cell segmentation is a common step in cell behavior analysis. Reliably and automatically segmenting cells in microscopy images remains challenging, especially in differential inference contrast microscopy images and phase-contrast microscopy images. ...
MOTIVATION: N7-methylguanosine (m7G) is an important epigenetic modification, playing an essential role in gene expression regulation. Therefore, accurate identification of m7G modifications will facilitate revealing and in-depth understanding their ...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.