AIMC Topic: Host-Pathogen Interactions

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Defining host-pathogen interactions employing an artificial intelligence workflow.

eLife Feb 12, 2019
UNLABELLED: For image-based infection biology, accurate unbiased quantification of host-pathogen interactions is essential, yet often performed manually or using limited enumeration employing simple image analysis algorithms based on image segmentati...
Humans Microscopy, Fluorescence Workflow Toxoplasma HeLa Cells Host-Pathogen Interactions Artificial Intelligence Single-Cell Analysis Image Processing, Computer-Assisted Salmonella typhimurium
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Systems Biology and Machine Learning in Plant-Pathogen Interactions.

Molecular plant-microbe interactions : MPMI Nov 12, 2018
Systems biology is an inclusive approach to study the static and dynamic emergent properties on a global scale by integrating multiomics datasets to establish qualitative and quantitative associations among multiple biological components. With an abu...
Systems Biology Models, Biological Host-Pathogen Interactions Machine Learning Algorithms Gene Regulatory Networks
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A multicentre verification study of the QuantiFERON-TB Gold Plus assay.

Tuberculosis (Edinburgh, Scotland) Nov 28, 2017
OBJECTIVES: The aim of this verification study was to compare the QuantiFERON-TB Gold Plus (QFT-Plus) to the QuantiFERON-TB Gold In Tube (QFT-GIT). The new QFT-Plus test contains an extra antigen tube which, according to the manufacturer additionally...
Interferon-gamma Release Tests CD4-Positive T-Lymphocytes Interferon-gamma Humans Male Latent Tuberculosis Female Middle Aged Belgium Mycobacterium tuberculosis Reproducibility of Results CD8-Positive T-Lymphocytes Antigens, Bacterial Netherlands Adult Predictive Value of Tests Host-Pathogen Interactions
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Three-dimensional visualization and a deep-learning model reveal complex fungal parasite networks in behaviorally manipulated ants.

Proceedings of the National Academy of Sciences of the United States of America Nov 7, 2017
Some microbes possess the ability to adaptively manipulate host behavior. To better understand how such microbial parasites control animal behavior, we examine the cell-level interactions between the species-specific fungal parasite and its carpente...
Muscles Animals Machine Learning Hypocreales Imaging, Three-Dimensional Host-Pathogen Interactions Mandible Ants Image Processing, Computer-Assisted Behavior, Animal
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iPHLoc-ES: Identification of bacteriophage protein locations using evolutionary and structural features.

Journal of theoretical biology Sep 21, 2017
Bacteriophage proteins are viruses that can significantly impact on the functioning of bacteria and can be used in phage based therapy. The functioning of Bacteriophage in the host bacteria depends on its location in those host cells. It is very impo...
Support Vector Machine Viral Proteins Intracellular Space Cell Compartmentation Evolution, Molecular Models, Biological Host-Pathogen Interactions Bacteriophages
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Acquaintance to Artificial Neural Networks and use of artificial intelligence as a diagnostic tool for tuberculosis: A review.

Tuberculosis (Edinburgh, Scotland) Sep 20, 2017
Tuberculosis [TB] has afflicted numerous nations in the world. As per a report by the World Health Organization [WHO], an estimated 1.4 million TB deaths in 2015 and an additional 0.4 million deaths resulting from TB disease among people living with ...
Biomarkers Reproducibility of Results Diagnosis, Computer-Assisted Fuzzy Logic Humans Neural Networks, Computer Decision Support Techniques Host-Pathogen Interactions Predictive Value of Tests Tuberculosis Mycobacterium tuberculosis Early Diagnosis
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Predicting Zoonotic Risk of Influenza A Viruses from Host Tropism Protein Signature Using Random Forest.

International journal of molecular sciences May 25, 2017
Influenza A viruses remain a significant health problem, especially when a novel subtype emerges from the avian population to cause severe outbreaks in humans. Zoonotic viruses arise from the animal population as a result of mutations and reassortmen...
Host-Pathogen Interactions Viral Proteins Orthomyxoviridae Infections Zoonoses Models, Theoretical Databases, Genetic Area Under Curve Influenza, Human Viral Tropism Host Specificity Machine Learning Retrospective Studies Reproducibility of Results Animals Disease Outbreaks Influenza in Birds Birds Influenza A virus Humans
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Bacterial Virus Ontology; Coordinating across Databases.

Viruses May 23, 2017
Bacterial viruses, also called bacteriophages, display a great genetic diversity and utilize unique processes for infecting and reproducing within a host cell. All these processes were investigated and indexed in the ViralZone knowledge base. To faci...
Host-Pathogen Interactions Terminology as Topic Bacteriophages Databases, Factual Biological Ontologies
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Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections.

Kidney international Mar 17, 2017
The immune system has evolved to sense invading pathogens, control infection, and restore tissue integrity. Despite symptomatic variability in patients, unequivocal evidence that an individual's immune system distinguishes between different organisms...
Peptide Mapping Peritonitis Peritoneal Dialysis Humans Pattern Recognition, Automated Machine Learning Host-Pathogen Interactions Biomarkers Adolescent Gram-Positive Bacterial Infections Female Time Factors Reproducibility of Results Gram-Negative Bacterial Infections ROC Curve Male Bacteria Acute Disease Aged Point-of-Care Systems Predictive Value of Tests Point-of-Care Testing Aged, 80 and over Middle Aged Area Under Curve Nonlinear Dynamics Young Adult Case-Control Studies Adult
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Prediction of virus-host infectious association by supervised learning methods.

BMC bioinformatics Mar 14, 2017
BACKGROUND: The study of virus-host infectious association is important for understanding the functions and dynamics of microbial communities. Both cellular and fractionated viral metagenomic data generate a large number of viral contigs with missing...
Genome, Viral Likelihood Functions Viruses Sequence Analysis, DNA Logistic Models Bayes Theorem Reproducibility of Results Models, Theoretical Metagenomics ROC Curve Support Vector Machine Bacteria Host-Pathogen Interactions DNA, Viral
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