NPJ primary care respiratory medicine
Nov 20, 2025
OBJECTIVE: This study explored the application of Machine Learning (ML) techniques to cluster patients with suspected sleep apnea (SA), based on clinical-demographic data, with the aim of optimizing diagnostic pathways and enabling more personalized ...
Primary myelofibrosis (PMF) is a heterogeneous bone marrow disorder, and substantial evidence indicates the involvement of inflammatory mediators in its progression. However, a diagnostic model based on inflammation-related genes has not yet been est...
This study presents a wearable robot equipped with a novel anchoring structure designed to improve both force transmission efficiency and user comfort. While soft wearable robots are inherently more comfortable than rigid exoskeletons, they often suf...
Mitochondrial autophagy (mitophagy) in macrophages is crucial yet poorly understood within the lung adenocarcinoma (LUAD) tumor microenvironment. This study aimed to identify key macrophage mitophagy-related genes and develop a robust prognostic mode...
OBJECTIVES: BMI and age are associated with the risk of osteoporosis (OP). The dynamic facial aging process involves changes in skin, muscle, fat, and facial bone structures, with facial skeletal aging affecting facial contours through volumetric red...
Brain network models offer insights into brain dynamics, but the utility of model-derived bifurcation parameters as biomarkers remains underexplored. This study evaluates bifurcation parameters from a whole-brain network model as biomarkers for disti...
Gliomas represent a heterogenous group of primary brain tumors with overlapping imaging phenotypes. Treatment typically includes surgery and/or chemoradiation, however this varies based on the overall lesion and clinical presentation. This heterogene...
Prostate cancer (PrCa) incidence and severity vary across ancestries; men of African ancestry (AA) are more likely to be diagnosed and die from PrCa than those of European ancestry (EA). Current polygenic risk scores, even from multi-ancestry GWAS, d...
Reservoir computers (RCs) are a class of recurrent neural networks that incorporate brain-inspired principles and provide an efficient alternative to deep learning. With fixed random internal connections and trained output weights, they simplify lear...
BACKGROUND: Digital tools are increasingly used to support clinical decision-making in dental education. However, the accuracy and efficiency of different support tools, including generative artificial intelligence, in the context of dental trauma ma...
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