AIMC Topic: Humans

Clear Filters Showing 2931 to 2940 of 95995 articles

Peripheral blood multimodal integration via cross-attention for cancer immune profiling.

BMC cancer
OBJECTIVE: Accurate cancer risk prediction is hindered by complex, multi-layered immune interactions, and traditional tissue biopsies are invasive and lack scalability for large-scale or repeated assessments. Peripheral blood offers a minimally invas...

Support vector machine-based preoperative identification of IDH-Mutant low-grade gliomas in adult gliomas using clinical features.

BMC neurology
BACKGROUND: The preoperative identification of (isocitrate dehydrogenase) IDH-mutant low-grade gliomas (LGGs) is critical for personalized treatment planning. We aimed to develop a streamlined machine-learning model using key clinical features for ra...

Cancer detection via one-shot learning: integrating gene expression and genomic mutation analysis.

BMC bioinformatics
BACKGROUND: Cancer is a complex disease influenced by numerous concurrent genetic factors that result in diverse tumor microenvironments (TMEs) across different cancer types. Large-scale genomic projects, such as The Cancer Genome Atlas, have undersc...

Predicting hematologic toxicity in advanced cervical cancer patients using interpretable machine learning models based on radiomics and dosimetrics.

BMC cancer
BACKGROUND AND OBJECTIVES: Hematologic toxicity (HT) is a common and serious side effect for advanced cervical cancer patients undergoing chemoradiotherapy. Accurately predicting HT can significantly improve patient management and treatment outcomes....

The Road to Precision Nanomedicine: An Insight on Drug Repurposing and Advances in Nanoformulations for Treatment of Cancer.

AAPS PharmSciTech
Cancer remains one of the most significant global health challenges, with its burden continuing to rise. The limitations of conventional anticancer therapies caused by the lack of tissue selectivity, demands urgent development of safer and more selec...

Single-cell RNA-sequencing of circulating tumour cells: A practical guide to workflow and translational applications.

Cancer metastasis reviews
The global burden of cancer is rising, with treatment failures often due to the metastatic nature of late-stage malignancies. Circulating tumour cells (CTCs) are metastatic precursors shed from primary tumours, which survive in circulation, extravasa...

Towards scalable and reliable coding of semantic property norms: ChatGPT vs. an improved AC-PLT.

Behavior research methods
When using the Property Listing Task (PLT) to collect semantic content for a set of concepts (Concept Property Norms, CPNs), coding raw properties into standardized labels poses significant challenges. In this work, we address these challenges by enh...

COVID-19 mortality and nutrition through predictive modeling and optimization based on grid search.

Scientific reports
Since 2019, humanity has been suffering from the negative impact of COVID-19, and the virus did not stop in its usual state but began to pivot to become more harmful until it reached its form now, which is the omicron variant. Therefore, in an attemp...

Machine learning-assisted screening of clinical features for predicting difficult-to-treat rheumatoid arthritis.

Scientific reports
To identify clinical features that predict the risk of meeting difficult-to-treat (D2T) rheumatoid arthritis (RA) definition in advance. This retrospective analysis included RA patients from the ATTRA registry who initiated biologic (b-) or targeted ...

Machine learning models to identify significant factors of panic buying situation.

Scientific reports
In panic-buying situations, individuals suddenly purchase excessive quantities of goods, leading to a massive crisis of essential goods in the market. As a result, many consumers cannot access the required products, creating an unstable societal situ...