AIMC Topic: Humans

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Proton range uncertainty caused by synthetic computed tomography generated with deep learning from pelvic magnetic resonance imaging.

Acta oncologica (Stockholm, Sweden)
BACKGROUND: In proton therapy, it is disputed whether synthetic computed tomography (sCT), derived from magnetic resonance imaging (MRI), permits accurate dose calculations. On the one hand, an MRI-only workflow could eliminate errors caused by, e.g....

Consistency in contouring of organs at risk by artificial intelligence vs oncologists in head and neck cancer patients.

Acta oncologica (Stockholm, Sweden)
BACKGROUND: In the Danish Head and Neck Cancer Group (DAHANCA) 35 trial, patients are selected for proton treatment based on simulated reductions of Normal Tissue Complication Probability (NTCP) for proton compared to photon treatment at the referrin...

Prognostic significance of cyclin D1 expression pattern in HPV-negative oral and oropharyngeal carcinoma: A deep-learning approach.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
BACKGROUND: We aimed to establish image recognition and survival prediction models using a novel scoring system of cyclin D1 expression pattern in patients with human papillomavirus-negative oral or oropharyngeal squamous cell carcinoma.

A foundation model for generalizable disease detection from retinal images.

Nature
Medical artificial intelligence (AI) offers great potential for recognizing signs of health conditions in retinal images and expediting the diagnosis of eye diseases and systemic disorders. However, the development of AI models requires substantial a...

The robot can break bars with the best of them: a novel approach to treating cricopharyngeal bars with myotomy.

Surgical endoscopy
INTRODUCTION: Failure of the cricopharyngeus to relax results in oropharyngeal dysphagia, which over time results in hypertrophy and increased risk for aspiration. Open myotomy is one definitive treatment option, however there are several drawbacks a...

Deep Learning Assisted Surface-Enhanced Raman Spectroscopy (SERS) for Rapid and Direct Nucleic Acid Amplification and Detection: Toward Enhanced Molecular Diagnostics.

ACS nano
Surface-enhanced Raman scattering (SERS) has evolved into a robust analytical technique capable of detecting a variety of biomolecules despite challenges in securing a reliable Raman signal. Conventional SERS-based nucleic acid detection relies on hy...

A robust deep learning workflow to predict CD8 + T-cell epitopes.

Genome medicine
BACKGROUND: T-cells play a crucial role in the adaptive immune system by triggering responses against cancer cells and pathogens, while maintaining tolerance against self-antigens, which has sparked interest in the development of various T-cell-focus...

Artificial intelligence-enhanced electrocardiography for early assessment of coronavirus disease 2019 severity.

Scientific reports
Despite challenges in severity scoring systems, artificial intelligence-enhanced electrocardiography (AI-ECG) could assist in early coronavirus disease 2019 (COVID-19) severity prediction. Between March 2020 and June 2022, we enrolled 1453 COVID-19 p...

Availability, Quality, and Evidence-Based Content of mHealth Apps for the Treatment of Nonspecific Low Back Pain in the German Language: Systematic Assessment.

JMIR mHealth and uHealth
BACKGROUND: Nonspecific low back pain (NSLBP) carries significant socioeconomic relevance and leads to substantial difficulties for those who are affected by it. The effectiveness of app-based treatments has been confirmed, and clinicians are recomme...

The spatial distribution of interleukin-4 (IL-4) reference values in China based on a back propagation (BP) neural network.

Geospatial health
This study aimed to investigate the geospatial distribution of normal reference values of Interleukin 4 (IL-4) in healthy Chinese adults and to provide a basis for the development of standard references. IL-4 values of 5,221 healthy adults from 64 ci...