The intrinsic complexity of biological processes often hides the role of dynamic microenvironmental cues in the development of pathological states. Microphysiological systems (MPSs) are emerging technological platforms that model dynamics of tissue-...
Journal of chemical information and modeling
Jul 25, 2025
Molecular carcinogenicity is a crucial factor in the development of cancer, and accurate prediction of it is vital for cancer prevention, treatment, and drug development. In recent years, deep learning has been applied to predict molecular carcinogen...
BACKGROUND: High intraoperative blood pressure variability (HIBPV) is significantly associated with postoperative adverse complications. However, practical tools to characterize perioperative factors associated with HIBPV remain limited. This study a...
BACKGROUND: Ultra-early detection of brain injury biomarkers within the critical first hour post-injury remains a major clinical challenge in mild traumatic brain injury (mTBI) management. Conventional platforms (e.g., ELISA) suffer from limited sens...
European journal of medicinal chemistry
Jul 24, 2025
Zeolitic imidazolate frameworks (ZIFs) exhibit exceptional properties such as high sensitivity, specificity, and biocompatibility, positioning them as promising materials for diagnosing and treating kidney diseases and diabetes. In kidney disease man...
International journal of pharmaceutics
Jul 24, 2025
This critical review provided a detailed strengths, weaknesses, opportunities, and threats (SWOT) analysis of nebulized liposomal formulations, focusing on the strengths and translational potential. The formulations have notable strengths, such as en...
Psychological resilience is influenced by both psychological and biological factors. However, the potential of using DNA methylation (DNAm) probes and brain imaging variables to predict psychological resilience remains unclear. This study aimed to in...
Micro- and nanoplastics (MNPs) are emerging pollutants that accumulate in ecosystems, food chains, and the human body, raising concerns about human health risks. However, understanding their toxicity remains challenging due to limited experimental da...
Neuroendocrine neoplasms (NENs) exemplify the challenges and opportunities inherent in managing rare cancers. Their rarity, biological heterogeneity, and diagnostic complexity necessitate a highly structured and multidisciplinary approach to patient ...
Primary large B-cell lymphomas of immune-privileged sites, including primary central nervous system lymphoma (PCNSL) and primary testicular lymphoma (PTL), exhibit distinct clinicopathologic features contributing to aggressive behavior and immune eva...
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