AIMC Topic: Humans

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Single-cell sequencing and machine learning reveal the role of dioxin-interacting genes in HCC prognosis and immune microenvironment.

Ecotoxicology and environmental safety
Dioxins are persistent environmental pollutants that bioaccumulate in the food chain, posing significant risks to human health. Despite their low environmental concentrations, dioxins accumulate in tissues, particularly in top predators and humans, r...

Contribution of Labrum and Cartilage to Joint Surface in Different Hip Deformities: An Automatic Deep Learning-Based 3-Dimensional Magnetic Resonance Imaging Analysis.

The American journal of sports medicine
BACKGROUND: Multiple 2-dimensional magnetic resonance imaging (MRI) studies have indicated that the size of the labrum adjusts in response to altered joint loading. In patients with hip dysplasia, it tends to increase as a compensatory mechanism for ...

Post-processing steps improve generalisability and robustness of an MRI-based radiogenomic model for human papillomavirus status prediction in oropharyngeal cancer.

European radiology
OBJECTIVES: To assess the impact of image post-processing steps on the generalisability of MRI-based radiogenomic models. Using a human papillomavirus (HPV) status in oropharyngeal squamous cell carcinoma (OPSCC) prediction model, this study examines...

Undergraduate Nursing Students' Perspectives on Artificial Intelligence in Academia.

The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres
With Artificial Intelligence (AI) tools becoming increasingly commonplace, the usage of AI-enabled tools in education has also grown. AI-enabled tools refer to machines incorporated with human-like capabilities, such as reasoning, interpretation, and...

Extending CARDIO:DE: Additional annotation guidelines and evaluation of NLP approaches for clinical applications.

International journal of medical informatics
BACKGROUND: Cardiovascular diseases are a major cause of morbidity and mortality, and the management of these conditions generates extensive clinical data. The CARDIO:DE dataset, a German-language corpus of cardiovascular clinical routine letters, ha...

Comparative analysis of AI algorithms on real medical data for chronic pain detection.

International journal of medical informatics
BACKGROUND AND OBJECTIVE: Chronic pain is a pervasive healthcare challenge with profound implications for patient well-being, clinical decision-making, and resource allocation. Traditional detection methods often rely on subjective assessments and ma...

A miniaturized liver function detection system with machine learning enhancing strategy.

Biosensors & bioelectronics
Serum alanine aminotransferase (ALT) is one of the most sensitive indicators of liver function and is crucial in diagnosing acute liver injury (ALI). However, its widespread clinical application is limited due to expensive equipment, detection delays...

Regulatory practices on the genotoxicity testing of nanomaterials and outlook for the future.

Regulatory toxicology and pharmacology : RTP
The toxicity of nanomaterials(NMs) is closely tied to their physicochemical properties, such as size, shape, surface chemistry, stability in biological medium, and state of agglomeration as well to their uptake by cells. Key deficiencies in standardi...

Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors.

Acta pharmacologica Sinica
GluN3A-containing NMDA receptors have recently emerged as promising therapeutic targets for neurological disorders. However, discovering potent modulators remains a significant challenge, primarily due to the limitations of traditional high-throughpu...

AI-guided spatiotemporal dispersion mapping for individualized ablation in an all-comer cohort with atrial fibrillation.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
BACKGROUND: Artificial intelligence (AI)-guided spatiotemporal dispersion (stD) mapping has been shown to improve outcomes in patients with persistent atrial fibrillation (AF). However, the relationship between stD mapping and markers of atrial cardi...