Humans

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Urinary bladder cancer staging in CT urography using machine learning.

Medical physics Sep 5, 2017
PURPOSE: To evaluate the feasibility of using an objective computer-aided system to assess bladder cancer stage in CT Urography (CTU).
Image Processing, Computer-Assisted Urinary Bladder Neoplasms Neoplasm Staging Urography Humans Machine Learning Tomography, X-Ray Computed
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Expression of AdipoR1 and AdipoR2 Receptors as Leptin-Breast Cancer Regulation Mechanisms.

Disease markers Sep 5, 2017
The development of breast cancer is influenced by the adipose tissue through the proteins leptin and adiponectin. However, there is little research concerning AdipoR1 and AdipoR2 receptors and the influence of leptin over them. The objective of this ...
Humans Female Breast Neoplasms Gene Expression Regulation, Neoplastic MCF-7 Cells Leptin Receptors, Adiponectin
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Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews.

Journal of healthcare engineering Sep 5, 2017
Adverse drug reactions (ADRs) are an essential part of the analysis of drug use, measuring drug use benefits, and making policy decisions. Traditional channels for identifying ADRs are reliable but very slow and only produce a small amount of data. T...
Natural Language Processing Drug-Related Side Effects and Adverse Reactions Pharmacovigilance Information Storage and Retrieval Young Adult Adult Male Middle Aged Humans Neural Networks, Computer Algorithms Female
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Machine learning techniques for the optimization of joint replacements: Application to a short-stem hip implant.

PloS one Sep 5, 2017
Today, different implant designs exist in the market; however, there is not a clear understanding of which are the best implant design parameters to achieve mechanical optimal conditions. Therefore, the aim of this project was to investigate if the g...
Humans Machine Learning Software Algorithms Computer Simulation Imaging, Three-Dimensional Decision Making Prosthesis Design Hip Prosthesis Weight-Bearing Arthroplasty, Replacement Stress, Mechanical Arthroplasty, Replacement, Hip Femur Finite Element Analysis
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Technologically-advanced assessment of upper-limb spasticity: a pilot study.

European journal of physical and rehabilitation medicine Sep 4, 2017
BACKGROUND: Spasticity is a muscle disorder associated with upper motor neuron syndrome occurring in neurological disorders, such as stroke, multiple sclerosis, spinal cord injury and others. It influences the patient's rehabilitation, interfering wi...
Sampling Studies Female Upper Extremity Aged Humans Male Stroke Rehabilitation Middle Aged Stroke Rehabilitation Centers Muscle Spasticity Pilot Projects Ambulatory Care Treatment Outcome Range of Motion, Articular Follow-Up Studies Task Performance and Analysis Robotics
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Fast Gaussian Naïve Bayes for searchlight classification analysis.

NeuroImage Sep 4, 2017
The searchlight technique is a variant of multivariate pattern analysis (MVPA) that examines neural activity across large sets of small regions, exhaustively covering the whole brain. This usually involves application of classifier algorithms across ...
(1)
Bayes Theorem Pattern Recognition, Automated Humans Brain Support Vector Machine Magnetic Resonance Imaging Brain Mapping
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From machine learning to deep learning: progress in machine intelligence for rational drug discovery.

Drug discovery today Sep 4, 2017
Machine intelligence, which is normally presented as artificial intelligence, refers to the intelligence exhibited by computers. In the history of rational drug discovery, various machine intelligence approaches have been applied to guide traditional...
(1)
Drug Discovery Models, Theoretical Quantitative Structure-Activity Relationship Humans Artificial Intelligence Machine Learning Drug Design
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Gene2DisCo: Gene to disease using disease commonalities.

Artificial intelligence in medicine Sep 4, 2017
OBJECTIVE: Finding the human genes co-causing complex diseases, also known as "disease-genes", is one of the emerging and challenging tasks in biomedicine. This process, termed gene prioritization (GP), is characterized by a scarcity of known disease...
(1)
Genetic Markers Data Mining Linear Models Toxicogenetics Machine Learning Humans Genetic Predisposition to Disease Algorithms Models, Genetic ROC Curve Databases, Genetic Gene Regulatory Networks Area Under Curve
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A Deep Learning-Based Radiomics Model for Prediction of Survival in Glioblastoma Multiforme.

Scientific reports Sep 4, 2017
Traditional radiomics models mainly rely on explicitly-designed handcrafted features from medical images. This paper aimed to investigate if deep features extracted via transfer learning can generate radiomics signatures for prediction of overall sur...
Female Reproducibility of Results Aged Aged, 80 and over Humans Prognosis Deep Learning Adolescent Child ROC Curve Young Adult Adult Male Middle Aged Glioblastoma Image Interpretation, Computer-Assisted Kaplan-Meier Estimate Image Processing, Computer-Assisted Nomograms Models, Theoretical Magnetic Resonance Imaging
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Multi-label Inductive Matrix Completion for Joint MGMT and IDH1 Status Prediction for Glioma Patients.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention Sep 4, 2017
MGMT promoter methylation and IDH1 mutation in high-grade gliomas (HGG) have proven to be the two important molecular indicators associated with better prognosis. Traditionally, the statuses of MGMT and IDH1 are obtained via surgical biopsy, which is...
(2)
Isocitrate Dehydrogenase DNA Modification Methylases Adult DNA Repair Enzymes Humans Tumor Suppressor Proteins Sensitivity and Specificity Female Middle Aged Algorithms Connectome Brain Neoplasms Glioma Reproducibility of Results Prognosis Male DNA Methylation Aged Mutation Young Adult
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