AIMC Topic: Hypoglycemic Agents

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Deep Diabetologist: Learning to Prescribe Hypoglycemic Medications with Recurrent Neural Networks.

Studies in health technology and informatics
In healthcare, applying deep learning models to electronic health records (EHRs) has drawn considerable attention. This sequential nature of EHR data make them wellmatched for the power of Recurrent Neural Network (RNN). In this poster, we propose "D...

Lactate levels and risk of lactic acidosis with metformin in diabetic kidney disease patients.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Metformin as an oral antidiabetic drug (OAD) is not recommended in renal failure due to the presumed risk of lactic acidosis though it has advantages in cardiovascular protection with a low risk of hypoglycemia. Few studies have measured lactic acid ...

Metformin Alleviates Lipopolysaccharide-induced Acute Lung Injury through Suppressing Toll-like Receptor 4 Signaling.

Iranian journal of allergy, asthma, and immunology
Signaling AMP-activated protein kinase (AMPK), an energy sensing enzyme, has been implicated in controlling inflammation. In this study we investigated whether activation of AMPK by metformin could protect the lung from lipopolysaccharide (LPS)-induc...

A Study of Applications of Machine Learning Based Classification Methods for Virtual Screening of Lead Molecules.

Combinatorial chemistry & high throughput screening
The ligand-based virtual screening of combinatorial libraries employs a number of statistical modeling and machine learning methods. A comprehensive analysis of the application of these methods for the diversity oriented virtual screening of biologic...