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Inflammation

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Pepsin Hydrolysate from Surimi Industry-Related Olive Flounder Head Byproducts Attenuates LPS-Induced Inflammation and Oxidative Stress in RAW 264.7 Macrophages and In Vivo Zebrafish Model.

Marine drugs
Fish head byproducts derived from surimi processing contribute about 15% of the total body weight, which are beneficial to health because they contain essential nutrients. In this study, olive flounder (OF) was the target species in order to maximize...

Association between neutrophil-to-lymphocyte ratio and diabetic kidney disease in type 2 diabetes mellitus patients: a cross-sectional study.

Frontiers in endocrinology
AIMS: This investigation examined the possibility of a relationship between neutrophil-to-lymphocyte ratio (NLR) and diabetic kidney disease (DKD) in type 2 diabetes mellitus (T2DM) patients.

Sex Differences in the Association Between Inflammation and Event-Free Survival in Patients With Heart Failure.

The Journal of cardiovascular nursing
BACKGROUND: Heart failure (HF) is associated with chronic inflammation, which is adversely associated with survival. Although sex-related differences in inflammation have been described in patients with HF, whether sex-related differences in inflamma...

Small immunological clocks identified by deep learning and gradient boosting.

Frontiers in immunology
BACKGROUND: The aging process affects all systems of the human body, and the observed increase in inflammatory components affecting the immune system in old age can lead to the development of age-associated diseases and systemic inflammation.

Diagnosis of Liver Fibrosis Using Artificial Intelligence: A Systematic Review.

Medicina (Kaunas, Lithuania)
The development of liver fibrosis as a consequence of continuous inflammation represents a turning point in the evolution of chronic liver diseases. The recent developments of artificial intelligence (AI) applications show a high potential for impro...

Blood-based biomarkers of chronic inflammation.

Expert review of molecular diagnostics
INTRODUCTION: Diseases related to chronic persisting inflammation are amongst the largest sources of morbidity and health costs, yet biomarkers for early diagnosis, prognosis, and treatment response are not sufficiently effective.

Chronic thromboembolic pulmonary hypertension: realising the potential of multimodal management.

The Lancet. Respiratory medicine
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute pulmonary embolism. Important advances have enabled better understanding, characterisation, and treatment of this condition. Guidelines recommending systematic foll...

Automated evaluation with deep learning of total interstitial inflammation and peritubular capillaritis on kidney biopsies.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
BACKGROUND: Interstitial inflammation and peritubular capillaritis are observed in many diseases on native and transplant kidney biopsies. A precise and automated evaluation of these histological criteria could help stratify patients' kidney prognose...

Predicting Anti-inflammatory Peptides by Ensemble Machine Learning and Deep Learning.

Journal of chemical information and modeling
Inflammation is a biological response to harmful stimuli, aiding in the maintenance of tissue homeostasis. However, excessive or persistent inflammation can precipitate a myriad of pathological conditions. Although current treatments such as NSAIDs, ...

Cracking the Code: The Role of Peripheral Nervous System Signaling in Fracture Repair.

Current osteoporosis reports
PURPOSE OF REVIEW: The traditionally understated role of neural regulation in fracture healing is gaining prominence, as recent findings underscore the peripheral nervous system's critical contribution to bone repair. Indeed, it is becoming more evid...