AIMC Topic: Insulin Resistance
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Effects of Dietary Approach to Stop Hypertension diet on androgens, antioxidant status and body composition in overweight and obese women with polycystic ovary syndrome: a randomised controlled trial.
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
Nov 7, 2016
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrine disease in reproductive age women. The present study aimed to determine the effects of Dietary Approaches to Stop Hypertension (DASH) diet on reproductive hormones, plasma tota...
Adaptations to excess choline in insulin resistant and Pcyt2 deficient skeletal muscle.
Biochemistry and cell biology = Biochimie et biologie cellulaire
Sep 6, 2016
It was hypothesized that choline supplementation in insulin resistant (IR) CTP:phosphoethanolamine cytidylyltransferase deficient (Pcyt2) mice would ameliorate muscle function by remodeling glucose and fatty acid (FA) metabolism. Pcyt2 mice either re...
RNA Nucleotidyltransferases
Microtubule-Associated Proteins
Administration, Oral
Signal Transduction
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Sterol Regulatory Element Binding Protein 1
Choline
Animals
Muscle, Skeletal
fas Receptor
Stearoyl-CoA Desaturase
Gene Expression Regulation
Mice
Mice, Knockout
Lipogenesis
Carnitine O-Palmitoyltransferase
PPAR alpha
Insulin Resistance
Glucose
Adaptation, Physiological
Diacylglycerol O-Acyltransferase
Triglycerides
Fatty Acids
Insulin Receptor Substrate Proteins
Organic Cation Transport Proteins
Adipokines, inflammatory mediators, and insulin-resistance parameters may not be good markers of metabolic syndrome after liver transplant.
Nutrition (Burbank, Los Angeles County, Calif.)
Dec 31, 2015
OBJECTIVE: The role of adipokines in liver transplantation (LTx) recipients who have metabolic syndrome (MetS) has seldom been assessed. The aim of this study was to investigate the concentrations of adipokines, inflammatory mediators, and insulin-re...
Interleukin-6
Biomarkers
Female
Cross-Sectional Studies
Male
Middle Aged
Postoperative Complications
Insulin Resistance
Metabolic Syndrome
C-Reactive Protein
Humans
Tumor Necrosis Factor-alpha
Adipokines
Chemokine CCL2
Resistin
Liver Transplantation
Inflammation Mediators
Adiponectin
Fatty Acids, Nonesterified
Relationship between vitamin D and body fat distribution evaluated by DXA in postmenopausal women.
Nutrition (Burbank, Los Angeles County, Calif.)
Dec 29, 2015
OBJECTIVE: The aim of this study was to explore the relationship between 25-hydroxyvitamin D (25[OH]D) serum concentrations and body fat distribution in a sample of postmenopausal women.
Effects of long-term folate supplementation on metabolic status and regression of cervical intraepithelial neoplasia: A randomized, double-blind, placebo-controlled trial.
Nutrition (Burbank, Los Angeles County, Calif.)
Dec 29, 2015
OBJECTIVE: This study was conducted to determine the effects of long-term folate supplementation on regression and metabolic status of patients with cervical intraepithelial neoplasia grade 1 (CIN1).
Cognitively impaired elderly exhibit insulin resistance and no memory improvement with infused insulin.
Neurobiology of aging
Dec 1, 2015
Insulin resistance is a risk factor for Alzheimer's disease (AD), although its role in AD etiology is unclear. We assessed insulin resistance using fasting and insulin-stimulated measures in 51 elderly subjects with no dementia (ND; n = 37) and with ...
Evaluation of insulin sensitivity temporal prediction by using quantile regression combined with neural network model.
International journal of medical informatics
Oct 1, 2025
BACKGROUND: Stress-induced hyperglycemia, a pathologically high blood glucose level, is a frequent complication in intensive care units. Blood glucose (BG) level control is crucial but challenging due to patient variability. The Stochastic TARgeted (...
Prediction of Insulin Resistance in Nondiabetic Population Using LightGBM and Cohort Validation of Its Clinical Value: Cross-Sectional and Retrospective Cohort Study.
JMIR medical informatics
Jun 13, 2025
BACKGROUND: Insulin resistance (IR), a precursor to type 2 diabetes and a major risk factor for various chronic diseases, is becoming increasingly prevalent in China due to population aging and unhealthy lifestyles. Current methods like the gold-stan...
Exploring the effect of the triglyceride-glucose index on bone metabolism in prepubertal children, a retrospective study: insights from traditional methods and machine-learning-based bone remodeling prediction.
PeerJ
Jan 1, 2025
BACKGROUND: Childhood obesity poses a significant risk to bone health, but the impact of insulin resistance (IR) on bone metabolism in prepubertal children, as assessed by the triglyceride-glucose (TyG) index, remains underexplored. Bone turnover mar...
Machine learning-based clustering identifies obesity subgroups with differential multi-omics profiles and metabolic patterns.
Obesity (Silver Spring, Md.)
Nov 1, 2024
OBJECTIVE: Individuals living with obesity are differentially susceptible to cardiometabolic diseases. We hypothesized that an integrative multi-omics approach might improve identification of subgroups of individuals with obesity who have distinct ca...
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