AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Lactic Acid

Showing 1 to 10 of 37 articles

Clear Filters

From data to decision: Machine learning determination of aerobic and anaerobic thresholds in athletes.

PloS one
Lactate analysis plays an important role in sports science and training decisions for optimising performance, endurance, and overall success in sports. Two parameters are widely used for these goals: aerobic (AeT) and anaerobic (AnT) thresholds. Howe...

Unravelling the metabolic landscape of cutaneous melanoma: Insights from single-cell sequencing analysis and machine learning for prognostic assessment of lactate metabolism.

Experimental dermatology
This manuscript presents a comprehensive investigation into the role of lactate metabolism-related genes as potential prognostic markers in skin cutaneous melanoma (SKCM). Bulk-transcriptome data from The Cancer Genome Atlas (TCGA) and GSE19234, GSE2...

Explainable machine learning-driven predictive performance and process parameter optimization for caproic acid production.

Bioresource technology
In this study, four machine learning (ML) prediction models were developed to predict and optimize the production performance of caproic acid based on substrates, products, and process parameters. The XGBoost outperformed others, with a high R of 0.9...

Imitating the respiratory activity of the brain stem by using artificial neural networks: exploratory study on an animal model of lactic acidosis and proof of concept.

Journal of clinical monitoring and computing
Artificial neural networks (ANNs) are versatile tools capable of learning without prior knowledge. This study aims to evaluate whether ANN can calculate minute volume during spontaneous breathing after being trained using data from an animal model of...

Quantification of L-lactic acid in human plasma samples using Ni-based electrodes and machine learning approach.

Talanta
This work presents a robust strategy for quantifying overlapping electrochemical signatures originating from complex mixtures and real human plasma samples using nickel-based electrochemical sensors and machine learning (ML). This strategy enables th...

Machine learning-based lactate-related genes signature predicts clinical outcomes and unveils novel therapeutic targets in esophageal squamous cell carcinoma.

Cancer letters
Esophageal squamous cell carcinoma (ESCC), a predominant subtype of esophageal cancer, typically presents with poor prognosis. Lactate is a crucial metabolite in cancer and significantly impacts tumor biology. Here, we aimed to construct a lactate-re...

Artificial Intelligence-Guided Identification of IGFBP7 as a Critical Indicator in Lactic Metabolism Determines Immunotherapy Response in Stomach Adenocarcinoma.

Journal of cellular and molecular medicine
Due to considerable tumour heterogeneity, stomach adenocarcinoma (STAD) has a poor prognosis and varies in response to treatment, making it one of the main causes of cancer-related mortality globally. Recent data point to a significant role for metab...

An assessment of machine learning methods to quantify blood lactate from neutrophils phagocytic activity.

Scientific reports
Phagocytosis is a critical component of innate immunity that helps the body defend itself against infection, foreign particles, and cellular debris. Investigating and quantifying phagocytosis can help understand how the immune system identifies forei...

Machine Learning Assisted-Intelligent Lactic Acid Monitoring in Sweat Supported by a Perspiration-Driven Self-Powered Sensor.

Nano letters
Lactic acid has aroused increasing attention due to its close association with serious diseases. A real-time, dynamic, and intelligent detection method is vital for sensitive detection of lactic acid. Here, a machine learning (ML)-assisted perspirati...

Machine learning integrated with in vitro experiments for study of drug release from PLGA nanoparticles.

Scientific reports
This paper investigates delivery of encapsulated drug from poly lactic-co-glycolic micro-/nano-particles. Experimental data collected from about 50 papers are analyzed by machine learning algorithms including linear regression, principal component an...