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Prediction of inherited genomic susceptibility to 20 common cancer types by a supervised machine-learning method.

Proceedings of the National Academy of Sciences of the United States of America
Prevention and early intervention are the most effective ways of avoiding or minimizing psychological, physical, and financial suffering from cancer. However, such proactive action requires the ability to predict the individual's susceptibility to ca...

Chemerin Blood Levels are Associated with MRI Measured Volumes of Abdominal Adipose Tissue Compartments and Lifestyle Choices.

Acta clinica Croatica
Obesity is a low-grade chronic inflammatory state, in which a cytokine chemerin with its immunometabolic modulation has an important role. We aimed to study in a healthy population relationships between serum chemerin levels, lifestyle choices and ma...

Visualization of Cancer and Cardiovascular Disease Co-Occurrence With Network Methods.

JCO clinical cancer informatics
PURPOSE: Cancer and cardiovascular disease (CVD) are common causes of morbidity and mortality, and measurement and interpretation of their co-occurrence rate have important implications for public health and patient care. Here, we present the raw and...

Prediction Effects of Personal, Psychosocial, and Occupational Risk Factors on Low Back Pain Severity Using Artificial Neural Networks Approach in Industrial Workers.

Journal of manipulative and physiological therapeutics
OBJECTIVES: This study aimed to provide an empirical model of predicting low back pain (LBP) by considering the occupational, personal, and psychological risk factor interactions in workers population employed in industrial units using an artificial ...

Reasoning and Data Representation in a Health and Lifestyle Support System.

Studies in health technology and informatics
Case-based reasoning and data interpretation is an artificial intelligence approach that capitalizes on past experience to solve current problems and this can be used as a method for practical intelligent systems. Case-based data reasoning is able to...

Analysis of the relation between health statistics and eating habits in Japanese prefectures using fuzzy robust regression model.

Computers in biology and medicine
In recent years, the Japanese Ministry of Health, Labour, and Welfare is working to improve citizen׳s lifestyle and social environment to improve their health. This is because of the following reasons. Diseases related to lifestyle such as malignant ...

Application of artificial neural networks to link genetic and environmental factors to DNA methylation in colorectal cancer.

Epigenomics
AIMS: We applied artificial neural networks (ANNs) to understand the connections among polymorphisms of genes involved in folate metabolism, clinico-pathological features and promoter methylation levels of MLH1, APC, CDKN2A(INK4A), MGMT and RASSF1A i...