AIMC Topic: Liquid Biopsy
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Global serum profiling: an opportunity for earlier cancer detection.
Journal of experimental & clinical cancer research : CR
Aug 15, 2023
The advances in cancer research achieved in the last 50 years have been remarkable and have provided a deeper knowledge of this disease in many of its conceptual and biochemical aspects. From viewing a tumor as a 'simple' aggregate of mutant cells an...
Uncovering cancer's secrets: could liquid biopsies and artificial intelligence hold the answers?
Future oncology (London, England)
Jun 15, 2023
Tweetable abstract How are #liquidbiopsies and #AI pushing us closer to the goal of early cancer detection for all? Plus, what more needs to be done to truly deciphers cancer's secrets? Find out in this editorial by @JadeParkerB.
Is There a Role for Machine Learning in Liquid Biopsy for Brain Tumors? A Systematic Review.
International journal of molecular sciences
Jun 3, 2023
The paucity of studies available in the literature on brain tumors demonstrates that liquid biopsy (LB) is not currently applied for central nervous system (CNS) cancers. The purpose of this systematic review focused on the application of machine lea...
Label-free liquid biopsy through the identification of tumor cells by machine learning-powered tomographic phase imaging flow cytometry.
Scientific reports
Apr 13, 2023
Image-based identification of circulating tumor cells in microfluidic cytometry condition is one of the most challenging perspectives in the Liquid Biopsy scenario. Here we show a machine learning-powered tomographic phase imaging flow cytometry syst...
Fluorescence Analysis of Circulating Exosomes for Breast Cancer Diagnosis Using a Sensor Array and Deep Learning.
ACS sensors
May 5, 2022
Emerging liquid biopsy methods for investigating biomarkers in bodily fluids such as blood, saliva, or urine can be used to perform noninvasive cancer detection. However, the complexity and heterogeneity of exosomes require improved methods to achiev...
[Moving towards a personalized oncology: The contribution of genomic techniques and artificial intelligence in the use of circulating tumor biomarkers].
Bulletin du cancer
Jan 13, 2022
Technological advances, in particular the development of high-throughput sequencing, have led to the emergence of a new generation of molecular biomarkers for tumors. These new tools have profoundly changed therapeutic management in oncology, with in...
Imaging and liquid biopsy in the prediction and evaluation of response to PRRT in neuroendocrine tumors: implications for patient management.
European journal of nuclear medicine and molecular imaging
Apr 26, 2021
PURPOSE: The aim of this narrative review is to give an overview on current and emerging imaging methods and liquid biopsy for prediction and evaluation of response to PRRT. Current limitations and new perspectives, including artificial intelligence,...
ALICE: a hybrid AI paradigm with enhanced connectivity and cybersecurity for a serendipitous encounter with circulating hybrid cells.
Theranostics
Sep 2, 2020
A fully automated and accurate assay of rare cell phenotypes in densely-packed fluorescently-labeled liquid biopsy images remains elusive. Employing a hybrid artificial intelligence (AI) paradigm that combines traditional rule-based morphological ma...
Neoplastic Cells, Circulating
Cell Count
Microscopy, Fluorescence
Internet of Things
Humans
Liquid Biopsy
Computer Security
Reproducibility of Results
Pancreatic Neoplasms
Aged
Predictive Value of Tests
Machine Learning
Biomarkers, Tumor
Male
Principal Component Analysis
Software
Middle Aged
Female
Image Processing, Computer-Assisted
A web-based automated machine learning platform to analyze liquid biopsy data.
Lab on a chip
May 18, 2020
Liquid biopsy (LB) technologies continue to improve in sensitivity, specificity, and multiplexing and can measure an ever growing library of disease biomarkers. However, clinical interpretation of the increasingly large sets of data these technologie...
Clinical Significance of Circulating Cardiomyocyte-Specific Cell-Free DNA in Patients With Heart Failure: A Proof-of-Concept Study.
The Canadian journal of cardiology
Oct 19, 2019
We investigated clinical significance of cell-free DNA (cfDNA) in heart failure. This study enrolled 32 heart failure patients and 28 control subjects. Total cfDNA levels were not different between groups (P = 0.343). Bisulfite-digital polymerase cha...
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