AIMC Topic: Lupus Erythematosus, Systemic
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Predicting hospital readmission for lupus patients: An RNN-LSTM-based deep-learning methodology.
Computers in biology and medicine
Aug 31, 2018
Hospital readmission is one of the critical metrics used for measuring the performance of hospitals. The HITECH Act imposes penalties when patients are readmitted to hospitals if they are diagnosed with one of the six conditions mentioned in the Act....
Diagnostic utility of serum melatonin levels in systemic lupus erythematosus: a case-control study.
Reumatismo
Dec 21, 2017
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune inflammatory disease and early diagnosis is of clinical and therapeutic importance. Melatonin is an endogenous endolamine hormone that plays an important role in the immune system du...
Characterizing Autoimmune Disease-associated Diffuse Large B-cell Lymphoma in a SEER-Medicare Cohort.
Clinical lymphoma, myeloma & leukemia
Dec 2, 2017
BACKGROUND: Severe immune dysregulation such as seen in autoimmune (AI) disease is known to act as a significant risk factor for diffuse large B-cell lymphoma (DLBCL). However, little is known about the demographics or clinical outcomes of DLBCL that...
Word2Vec inversion and traditional text classifiers for phenotyping lupus.
BMC medical informatics and decision making
Aug 22, 2017
BACKGROUND: Identifying patients with certain clinical criteria based on manual chart review of doctors' notes is a daunting task given the massive amounts of text notes in the electronic health records (EHR). This task can be automated using text cl...
Antiphospholipid Antibodies and Heart Valve Disease in Systemic Lupus Erythematosus.
The American journal of the medical sciences
Jul 20, 2017
Evaluation of antiphospholipid antibodies (aPL) and correlation with heart valve abnormalities among patients with systemic lupus erythematosus (SLE). Nested case-control study was conducted with 70 patients with SLE selected from a longitudinal data...
Adolescent
Logistic Models
Aortic Valve Stenosis
Tricuspid Valve Insufficiency
Lupus Erythematosus, Systemic
Odds Ratio
Male
Humans
Mitral Valve Insufficiency
Heart Valve Prosthesis
Echocardiography
Female
Aortic Valve Insufficiency
Antibodies, Antiphospholipid
Middle Aged
Young Adult
Heart Valve Diseases
Mitral Valve Stenosis
Case-Control Studies
Adult
Multivariate Analysis
Ozone decreases sperm quality in systemic lupus erythematosus patients.
Revista brasileira de reumatologia
Nov 23, 2015
OBJECTIVE: To investigate the deleterious effects of air pollutants exposure in the Sao Paulo metropolitan region on semen quality in systemic lupus erythematosus (SLE).
IgA nephropathy in systemic lupus erythematosus patients: case report and literature review.
Revista brasileira de reumatologia
Feb 16, 2015
Systemic erythematosus lupus (SLE) is a multisystemic autoimmune disease which has nephritis as one of the most striking manifestations. Although it can coexist with other autoimmune diseases, and determine the predisposition to various infectious co...
Multifactor dimensionality reduction analysis to elucidate the cross-talk between one-carbon and xenobiotic metabolic pathways in multi-disease models.
Molecular biology reports
Feb 4, 2015
Putatively functional polymorphisms of one-carbon and xenobiotic metabolic pathways influence susceptibility for wide spectrum of diseases. The current study was aimed to explore gene-gene interactions among these two metabolic pathways in four disea...
Xenobiotics
Epistasis, Genetic
Oxidoreductases
Transferases
Multifactor Dimensionality Reduction
Parkinson Disease
Metabolic Networks and Pathways
Factor Analysis, Statistical
Lupus Erythematosus, Systemic
Coronary Artery Disease
Sex Factors
Datasets as Topic
Gene Expression Regulation
Case-Control Studies
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide
Carbon
Humans
Female
Breast Neoplasms
Male
First nomogram for predicting interstitial lung disease and pulmonary arterial hypertension in SLE: a machine learning approach.
Respiratory research
May 24, 2025
BACKGROUND: Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) are severe, life-threatening complications of systemic lupus erythematosus (SLE). Early identification of high-risk patients remains challenging due to the lack of ...
scPrediXcan integrates deep learning methods and single-cell data into a cell-type-specific transcriptome-wide association study framework.
Cell genomics
May 14, 2025
Transcriptome-wide association studies (TWASs) help identify disease-causing genes but often fail to pinpoint disease mechanisms at the cellular level because of the limited sample sizes and sparsity of cell-type-specific expression data. Here, we pr...
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