We use machine learning to identify innovative strategies to target azithromycin to the children with watery diarrhea who are most likely to benefit. Using data from a randomized trial of azithromycin for watery diarrhea (NCT03130114), we develop per...
Clinical notes should capture important information from a physician-patient encounter, but they may also contain signals indicative of physician fatigue. Using data from 129,228 emergency department (ED) visits, we train a model to identify notes wr...
Reactive oxygen species (ROS) are highly reactive molecules encountered by yeasts during routine metabolism and during interactions with other organisms, including host infection. Here, we characterize the variation in resistance to the ROS-inducing ...
PURPOSE: Pancreatic cancer (PC) is one of the most lethal malignancies, often presenting with nonspecific symptoms and a dismal prognosis. Despite advancements in treatments, the 5-year survival rate remains low, highlighting the urgent need for effe...
Artificial intelligence (AI) has been applied to early recognition and management of rapidly progressive, community-acquired pediatric sepsis, a leading cause of childhood mortality. The broad adoption of electronic health records combined with rapid...
AIMS: BoneFinder is a machine-learning tool that can automatically calculate Reimers migration percentage (RMP) and head-shaft angle (HSA) from paediatric cerebral palsy (CP) pelvic radiographs. This study's primary aim was to compare BoneFinder's fu...
BACKGROUND: The integration of machine learning and deep learning methodologies has transformed data analytics in biomechanics. However, the field faces challenges such as limited large-scale data sets, high data acquisition costs, and restricted par...
Blood-based biomarkers in epilepsy could constitute important research tools advancing neurobiological understanding and valuable clinical tools for better diagnosis and follow-up. An interesting question is whether biomarker patterns could contribut...
BACKGROUND: Acute kidney injury (AKI) and acute kidney disease (AKD) are frequent complications of hospitalization, resulting in reduced outcomes and increased cost burden. However, these conditions are only sometimes recognized and promptly treated....
Heart attack detection and treatment in women remain significantly under-optimized due to differences in symptom presentation and physiological characteristics compared to men, leading to delayed or incorrect diagnoses. Addressing this gap, this stud...
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