The production of recombinant therapeutic proteins from animal or human cell lines entails the risk of endogenous viral contamination from cell substrates and adventitious agents from raw materials and environment. One of the approaches to control su...
Clinical cancer research : an official journal of the American Association for Cancer Research
Feb 24, 2021
PURPOSE: Nodule evaluation is challenging and critical to diagnose multiple pulmonary nodules (MPNs). We aimed to develop and validate a machine learning-based model to estimate the malignant probability of MPNs to guide decision-making.
OBJECTIVE: We sought to identify an abbreviated test of impaired olfaction amenable for use in busy clinical environments in prodromal (isolated REM sleep behavior disorder [iRBD]) and manifest Parkinson disease (PD).
Annals of clinical and translational neurology
Feb 24, 2021
OBJECTIVE: No relapse risk prediction tool is currently available to guide treatment selection for multiple sclerosis (MS). Leveraging electronic health record (EHR) data readily available at the point of care, we developed a clinical tool for predic...
Speech emotion recognition (SER) is a natural method of recognizing individual emotions in everyday life. To distribute SER models to real-world applications, some key challenges must be overcome, such as the lack of datasets tagged with emotion labe...
BACKGROUND: Identifying cognitive impairment early enough could support timely intervention that may hinder or delay the trajectory of cognitive impairment, thus increasing the chances for successful cognitive aging.
Neural networks : the official journal of the International Neural Network Society
Feb 23, 2021
We derive the fast convergence rates of a deep neural network (DNN) classifier with the rectified linear unit (ReLU) activation function learned using the hinge loss. We consider three cases for a true model: (1) a smooth decision boundary, (2) smoot...
OBJECTIVE: To introduce local binary pattern (LBP) texture analysis to cartilage osteoarthritis (OA) research and compare the performance of different classification systems in discrimination of OA subjects from healthy controls using gray-level co-o...
Background CT colonography does not enable definite differentiation between benign and premalignant colorectal polyps. Purpose To perform machine learning-based differentiation of benign and premalignant colorectal polyps detected with CT colonograph...
A prerequisite for intelligent behavior is to understand how stimuli are related and to generalize this knowledge across contexts. Generalization can be challenging when relational patterns are shared across contexts but exist on different physical s...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.