Obstetric ultrasound examination of physiological parameters has been mainly used to estimate the fetal weight during pregnancy and baby weight before labour to monitor fetal growth and reduce prenatal morbidity and mortality. However, the problem is...
Tropical animal health and production
Nov 15, 2019
This study is concerned with developing predictive models using machine learning techniques to be used in identifying factors that influence farmers' decisions, predict farmers' decisions, and forecast farmers' demands relating to breeding service. T...
Protein structure prediction has long been available as an alternative to experimental structure determination, especially via homology modeling based on templates from related sequences. Recently, models based on distance restraints from coevolution...
We applied genetic programming approaches to understand the impact of descriptors on inhibitory effects of serine protease inhibitors of () and the discovery of new inhibitors as drug candidates. The experimental dataset of serine protease inhibit...
Liver disease causes millions of deaths per year worldwide, and approximately half of these cases are due to cirrhosis, which is an advanced stage of liver fibrosis that can be accompanied by liver failure and portal hypertension. Early detection of ...
BACKGROUND: Current guidelines recommend surgical resection as the first-line option for patients with solitary hepatocellular carcinoma (HCC); unfortunately, postoperative recurrence rate remains high and there is no reliable prediction tool. We exp...
Journal of computer-aided molecular design
Nov 15, 2019
Cathepsin S (CatS), a member of cysteine cathepsin proteases, has been well studied due to its significant role in many pathological processes, including arthritis, cancer and cardiovascular diseases. CatS inhibitors have been included in D3R-GC3 for...
Deep-UV (DUV) excitation fluorescence microscopy has potential to provide rapid diagnosis with simple technique comparing to conventional histopathology based on hematoxylin and eosin (H&E) staining. We established a fluorescent staining protocol for...
We introduce machine learning (ML) to perform classification and quantitation of images of nuclei from human blood neutrophils. Here we assessed the use of convolutional neural networks (CNNs) using free, open source software to accurately quantitate...
Machine learning (ML) is ubiquitous in bioinformatics, due to its versatility. One of the most crucial aspects to consider while training a ML model is to carefully select the optimal feature encoding for the problem at hand. Biophysical propensity s...
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