The escalating global environmental crisis demands transformative biotechnological solutions that are both sustainable and scalable. This perspective advocates Data-Driven Synthetic Microbes (DDSM); engineered microorganisms designed through integrat...
Cellular senescence is an irreversible state of cell cycle arrest with a complex role in tissue repair, aging, and disease. However, inconsistencies in identifying cellular senescence have led to varying conclusions about their functional significanc...
OBJECTIVES: To identify and characterise distinct subgroups of patients with asthma with severe acute exacerbations (AEs) by using a multistep clustering methodology that combines supervised and unsupervised machine learning.
BACKGROUND AND PURPOSE: We aimed to externally validate machine learning models developed in Norway by evaluating their predictive outcome of disability and pain 12 months after lumbar disc herniation surgery in a Swedish and Danish cohort.
BACKGROUND AND PURPOSE: Treatment-related shared decision-making (SDM) in older adults with hip fractures is complex due to the need to balance patient-specific factors such as life goals, frailty, and surgical risks. It includes considerations such...
INTRODUCTION: Malaria remains a significant public health challenge in Ethiopia, with over 7.3 million cases and 1,157 deaths reported between January 1 and October 20, 2024. Despite extensive distribution campaigns, 35% of insecticide-treated nets (...
BACKGROUND: End-Stage Renal Disease (ESRD) is a severe chronic kidney disease with a rising global incidence, often accompanied by various complications, severely impacting patients' quality of life. Parthanatos plays a crucial role in the pathogenes...
Journal of pharmaceutical and biomedical analysis
Jul 6, 2025
Ginger-processed Eucommiae Cortex (G-EC) is a traditional herbal preparation with a long history of clinical application. However, the lack of quantitative standards, undefined chemical transformation pathways, and unidentified quality markers (Q-mar...
European journal of medicinal chemistry
Jul 6, 2025
Machine learning (ML) has become very popular, and its benefits are widely recognized within the scientific community. The ability of ML approaches to leverage large datasets to find patterns among composite single data points has made these approach...
Journal of chemical information and modeling
Jul 6, 2025
Artificial intelligence (AI) plays a significant role in advancing polymer science and engineering. Considering the critical role of the glass transition temperature () in determining the physical properties of polymers, this study systematically inv...
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