Journal of computer-aided molecular design
Jul 6, 2025
The PI3K/Akt pathway plays a crucial role in regulating a broad network of proteins involved in the proliferation of HER2-positive breast cancer. The ethyl acetate fraction of Vernonia amygdalina, which contains cardiac glycosides, has been shown to ...
Prostate cancer bone metastasis (PCBM) is a highly lethal condition with limited survival. Accurate survival prediction is essential for managing these typically incurable patients. However, existing clinical models lack precision. This study seeks t...
INTRODUCTION: Suction devices such as flexible and navigable suction ureteral access sheath (FANS) are promising tools to reach the zero-fragment rate (ZFR) after flexible ureteroscopy (FURS) and laser lithotripsy. FANS could especially be useful for...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jul 5, 2025
Bone infections, such as fracture-related and periprosthetic joint infections, present significant diagnostic and therapeutic challenges in orthopaedic surgery. Current diagnosic standards rely primarily on tissue cultures of intraoperatively obtaine...
BACKGROUND: Crohn's disease (CD) is a chronic inflammatory bowel disease, with infliximab (IFX) commonly used for treatment. However, no clinically applicable model currently exists to predict the response of patients with CD to IFX therapy. Given th...
Air pollution remains a critical public health and environmental challenge, particularly in urban areas where traffic emissions and meteorological conditions strongly influence air quality. While Machine Learning (ML) techniques have been increasingl...
European journal of cancer (Oxford, England : 1990)
Jul 5, 2025
BACKGROUND: Cancer recurrence and progression, once seen as markers of poor prognosis, are now considered manageable aspects of long-term care. Advances in treatment have extended survival, emphasizing the need for representative epidemiological info...
BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD), a progressively worsening respiratory condition, severely impacts patient quality of life. Early risk assessment can improve treatment outcomes and lessen healthcare burdens. How...
BACKGROUND: Poly-victimization (PV), encompassing multiple forms of victimization including physical abuse, emotional maltreatment, neglect, and peer violence, poses a significant public health challenge among children, particularly in rural areas wi...
This study assesses the influence of social support, self-esteem, depression, and education on psychological resilience among men who have sex with men (MSM) to inform policy-making. Data were collected from 1,070 MSM via an online survey in Zhejiang...
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