AIMC Topic: Machine Learning

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Exploring Ovarian Cancer Prediction Models and Potential Markers Using Machine Learning.

Annals of clinical and laboratory science
OBJECTIVE: To develop machine learning models, facilitate a more accurate diagnosis of ovarian cancer (OC), and explore potential markers.

Machine Learning in Drug Development for Neurological Diseases: A Review of Blood Brain Barrier Permeability Prediction Models.

Molecular informatics
The blood brain barrier (BBB) is an endothelial-derived structure which restricts the movement of certain molecules between the general somatic circulatory system to the central nervous system (CNS). While the BBB maintains homeostasis by regulating ...

Using pretrained models in ensemble learning for date fruits multiclass classification.

Journal of food science
Date fruits are a primary agricultural product that comes in a variety of textures, colors, and tastes; hence, the correct classification is crucial for quality control, automatic sorting, and commercial applications. Deep learning has surely shown c...

A Machine Learning Model for Diagnosing Opportunistic Infections in HIV Patients: Broad Applicability Across Infection Types.

Journal of cellular and molecular medicine
Opportunistic infections (OIs) are the leading cause of hospitalisation and mortality among Human Immunodeficiency Virus-infected (HIV-infected) patients. The diverse pathogen types and intricate clinical manifestations associated present a formidabl...

Machine Learning-Based Glycolipid Metabolism Gene Signature Predicts Prognosis and Immune Landscape in Oesophageal Squamous Cell Carcinoma.

Journal of cellular and molecular medicine
Using machine learning approaches, we developed and validated a novel prognostic model for oesophageal squamous cell carcinoma (ESCC) based on glycolipid metabolism-related genes. Through integrated analysis of TCGA and GEO datasets, we established a...

Machine Learning Models Based on Stretched-Exponential Diffusion Weighted Imaging to Predict TROP2 Expression in Nude Mouse Breast Cancer Models.

Discovery medicine
BACKGROUND: Trophoblast cell surface antigen 2 (TROP2) is a promising target for various cancers, including breast cancer. The development of noninvasive techniques for assessing TROP2 expression in tumors holds considerable importance. This study ai...

Comparing Explanations of Molecular Machine Learning Models Generated with Different Methods for the Calculation of Shapley Values.

Molecular informatics
Feature attribution methods from explainable artificial intelligence (XAI) provide explanations of machine learning models by quantifying feature importance for predictions of test instances. While features determining individual predictions have fre...

Predicting amyloid beta accumulation in cognitively unimpaired older adults: Cognitive assessments provide no additional utility beyond demographic and genetic factors.

Alzheimer's & dementia : the journal of the Alzheimer's Association
BACKGROUND: Integrating non-invasive measures to estimate abnormal amyloid beta accumulation (Aβ+) is key to developing a screening tool for preclinical Alzheimer's disease (AD). The predictive capability of standard neuropsychological tests in estim...

Identifying Lipid Metabolism-Related Therapeutic Targets and Diagnostic Markers for Lung Adenocarcinoma by Mendelian Randomization and Machine Learning Analysis.

Thoracic cancer
BACKGROUND: Lipid metabolic disorders are emerging as a recognized influencing factors of lung adenocarcinoma (LUAD). This study aims to investigate the influence of lipid metabolism-related genes (LMRGs) on the diagnosis and treatment of LUAD and to...

Application of Interpretable Machine Learning Models to Predict the Risk Factors of HBV-Related Liver Cirrhosis in CHB Patients Based on Routine Clinical Data: A Retrospective Cohort Study.

Journal of medical virology
Chronic hepatitis B (CHB) infection represents a significant global public health issue, often leading to hepatitis B virus (HBV)-related liver cirrhosis (HBV-LC) with poor prognoses. Early identification of HBV-LC risk is essential for timely interv...