AIMC Topic: Machine Learning

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Molecular features and diagnostic modeling of synovium- and IPFP-derived OA macrophages in the inflammatory microenvironment via scRNA-seq and machine learning.

Journal of orthopaedic surgery and research
BACKGROUND: Osteoarthritis (OA) is the leading cause of degenerative joint disease, with total joint replacement as the only definitive cure. However, no disease-modifying therapy is currently available. Inflammation and fibrosis in the infrapatellar...

Predicting depression and unravelling its heterogeneous influences in middle-aged and older people populations: a machine learning approach.

BMC psychology
BACKGROUND: Aging has become a global trend, and depression, as an accompanying issue, poses a significant threat to the health of middle-aged and older adults. Existing studies primarily rely on statistical methods such as logistic regression for sm...

A machine learning-based framework for predicting postpartum chronic pain: a retrospective study.

BMC medical informatics and decision making
BACKGROUND: Postpartum chronic pain is prevalent, affecting many women after delivery. Machine learning algorithms have been widely used in predicting postoperative conditions. We investigated the prevalence of and risk factors for postpartum chronic...

Automated machine learning for early prediction of systemic inflammatory response syndrome in acute pancreatitis.

BMC medical informatics and decision making
BACKGROUND: Systemic inflammatory response syndrome (SIRS) is a frequent and serious complication of acute pancreatitis (AP), often associated with increased mortality. This study aims to leverage automated machine learning (AutoML) algorithms to cre...

Machine learning-based characterization of stemness features and construction of a stemness subtype classifier for bladder cancer.

BMC cancer
BACKGROUND: Bladder cancer (BLCA) is a highly heterogeneous disease that presents challenges in predicting prognosis and treatment response. Cancer stem cells are key drivers of tumor development, progression, metastasis, and treatment resistance. Th...

Predicting coronary heart disease with advanced machine learning classifiers for improved cardiovascular risk assessment.

Scientific reports
Worldwide, coronary heart disease (CHD) is a leading cause of mortality, and its early prediction remains a critical challenge in clinical data analysis. Machine learning (ML) offers valuable diagnostic support by leveraging healthcare data to enhanc...

Machine learning center-specific models show improved IVF live birth predictions over US national registry-based model.

Nature communications
Expanding in vitro fertilization (IVF) access requires improved patient counseling and affordability via cost-success transparency. Clinicians ask how two types of live birth prediction (LBP) models perform: machine learning, center-specific (MLCS) m...

Validation of a machine learning algorithm for identifying infants at risk of hypoxic ischaemic encephalopathy in a large unseen data set.

Archives of disease in childhood. Fetal and neonatal edition
OBJECTIVE: To validate a hypoxic ischaemic encephalopathy (HIE) prediction algorithm to identify infants at risk of HIE immediately after birth using readily available clinical data.

Predicting Powder Blend Flowability from Individual Constituent Properties Using Machine Learning.

Pharmaceutical research
PURPOSE: Predicting powder blend flowability is necessary for pharmaceutical manufacturing but challenging and resource-intensive. The purpose was to develop machine learning (ML) models to help predict flowability across multiple flow categories, id...

Comprehensive molecular analyses of an autoimmune-related gene predictive model and immune infiltrations using machine learning methods in intracranial aneurysma.

Frontiers in immunology
BACKGROUND: Increasing evidence indicates a connection between intracranial aneurysm (intracranial aneurysm, IA) and autoimmune diseases. However, the molecular mechanisms from a genetic perspective remain unclear. This study aims to elucidate the po...