AIMC Topic: Machine Learning

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Identification of CACNB1 protein as an actionable therapeutic target for hepatocellular carcinoma via metabolic dysfunction analysis in liver diseases: An integrated bioinformatics and machine learning approach for precise therapy.

International journal of biological macromolecules
In addition to histological evaluation for nonalcoholic fatty liver disease (NAFLD), a comprehensive analysis of the metabolic landscape is urgently needed to categorize patients into distinct subgroups for precise treatment. In this study, a total o...

A Machine Learning Approach to Predict Cognitive Decline in Alzheimer Disease Clinical Trials.

Neurology
BACKGROUND AND OBJECTIVES: Among the participants of Alzheimer disease (AD) treatment trials, 40% do not show cognitive decline over 80 weeks of follow-up. Identifying and excluding these individuals can increase power to detect treatment effects. We...

Post-Anesthesia Care Unit (PACU) readiness predictions using machine learning: a comparative study of algorithms.

BMC medical informatics and decision making
INTRODUCTION: Accurate and timely discharge from the Post-Anesthesia Care Unit (PACU) is essential to prevent postoperative complications and optimize hospital resource utilization. Premature discharge can lead to severe issues such as respiratory or...

Machine learning prediction of preterm birth in women under 35 using routine biomarkers in a retrospective cohort study.

Scientific reports
Preterm birth (PTB), defined as delivery before 37 weeks, affects 15 million infants annually, accounting for 11% of live births and over 35% of neonatal deaths. While advanced maternal age (≥ 35 years) is a known risk factor, PTB risk in women under...

Enhanced diagnosis of multi-drug-resistant microbes using group association modeling and machine learning.

Nature communications
New solutions are needed to detect genotype-phenotype associations involved in microbial drug resistance. Herein, we describe a Group Association Model (GAM) that accurately identifies genetic variants linked to drug resistance and mitigates false-po...

Predicting Therapy Outcomes in Patients With Stress-Related Disorders: Protocol for a Predictive Modeling Study.

JMIR research protocols
BACKGROUND: While cognitive behavioral therapy has shown efficacy in treating stress-related disorders, such as adjustment disorder and exhaustion disorder, knowledge about factors contributing to treatment response is limited. Improved identificatio...

Assessing potential toxic metal threats in tea growing soils of India with soil health indices and machine learning technologies.

Environmental monitoring and assessment
This study explores the impact of potentially toxic metals (PTMs) contamination in Indian tea-growing soils on ecosystems, soil quality, and human health using machine learning and statistical analysis. A total of 148 surface soil samples were collec...

Select for better learning: identifying high-quality training data for a multimodal cyclic transformer.

Journal of neural engineering
. Tonic-clonic seizures (TCSs), which present a significant risk for sudden unexpected death in epilepsy, require accurate detection to enable effective long-term monitoring. Previous studies have demonstrated the advantages of multimodal seizure det...