Journal of chemical information and modeling
Mar 19, 2025
Abdominal aortic aneurysm (AAA) is a life-threatening disorder with limited therapeutic options. Neutrophil extracellular traps (NETs) are formed by a process known as "NETosis" that has been implicated in AAA pathogenesis, yet the roles and prognost...
ACS biomaterials science & engineering
Mar 19, 2025
Effective drug development for bone-related diseases, such as osteoporosis and metastasis, is hindered by the lack of physiologically relevant in vitro models. Traditional platforms, including standard tissue culture plastic, fail to replicate the st...
INTRODUCTION: The landscape of early drug discovery is rapidly evolving, fueled by significant advancements in artificial intelligence (AI) and machine learning (ML), which are transforming the way drugs are discovered. As traditional drug discovery ...
INTRODUCTION: Prostate cancer (PCa) is a leading cause of cancer-related deaths among men, and accurate diagnosis is critical for effective management. Multiparametric MRI (mpMRI) has become an essential tool in PCa diagnosis due to its superior spat...
Stroke is a leading cause of death and disability in developed countries. We validated an AI-based prediction model for incident stroke using sensors such as fundus cameras and ophthalmoscopes for retinal images, along with socio-demographic data and...
BACKGROUND: Postoperative pulmonary infection (POI) is strongly associated with a poor prognosis and has a high incidence in elderly patients undergoing major surgery. Machine learning (ML) algorithms are increasingly being used in medicine, but the ...
BACKGROUND: To evaluate the predictive utility of machine learning and nomogram in predicting in-hospital mortality in patients with acute myocardial infarction complicated by cardiogenic shock (AMI-CS), and to visualize the model results in order to...
OBJECTIVE: The purpose of the current study is to explore the value of a nomogram that integrates clinical factors and MRI white matter hyperintensities (WMH) radiomics features in predicting the prognosis at 90 days for patients with acute ischemic ...
OBJECTIVE: This study aims to investigate the influencing factors of pregnancy outcomes during in vitro fertilization and embryo transfer (IVF-ET) procedures in clinical practice. Several prediction models were constructed to predict pregnancy outcom...
BACKGROUND: Low birth weight (LBW) is a critical factor linked to neonatal morbidity and mortality. Early prediction is essential for timely interventions. This study aimed to develop and evaluate predictive models for LBW using machine learning algo...
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