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Identification of genes related to the effects of bicalutamide and zoladex on benign prostatic hyperplasia.

Scientific reports
Existing research indicates that bicalutamide and zoladex show significant potential in treating prostate cancer. However, in the clinical application of treating benign prostatic hyperplasia (BPH), it is limited due to relatively severe side effects...

MRI grading of lumbar disc herniation based on AFFM-YOLOv8 system.

Scientific reports
Magnetic resonance imaging (MRI) serves as the clinical gold standard for diagnosing lumbar disc herniation (LDH). This multicenter study was to develop and clinically validate a deep learning (DL) model utilizing axial T2-weighted lumbar MRI sequenc...

Development and validation of a machine learning model for cardiovascular disease risk prediction in type 2 diabetes patients.

Scientific reports
Patients with type 2 diabetes mellitus (T2DM) have a significantly higher risk of cardiovascular disease (CVD) compared to the general population. Accurately predicting this risk is crucial for developing personalized treatment plans and public healt...

Impact of AI-quantified fluid dynamics on visual outcomes over 5 years in patients with treatment-naïve nAMD from the FRB! registry.

Scientific reports
To investigate the impact of retinal fluid dynamics on visual outcomes in patients with treatment-naïve neovascular age-related macular degeneration (nAMD) treated in the real world over 5 years using approved AI-based fluid monitoring. Real-world da...

Consistency verification and interpretation of explainable AI for predicting annual home runs of professional baseball players from sensor data.

Scientific reports
This study aimed to verify and interpret a model for predicting the number of home runs per year using sensor data from professional baseball players during batting practice. A machine learning model was constructed using Random Forest from the bat k...

Non-invasive detection of choroidal melanoma via tear-derived protein corona on gold nanoparticles: a machine learning approach.

Scientific reports
This study investigates the feasibility of using tear sample analysis, based on protein corona formation on gold nanoparticles combined with electrospray ionization mass spectrometry (ESI-MS) and machine learning techniques, as a non-invasive approac...

A multinational study of deep learning-based image enhancement for multiparametric glioma MRI.

Scientific reports
This study aimed to validate the utility of commercially available vendor-neutral deep learning (DL) image enhancement software for improving the image quality of multiparametric MRI for gliomas in a multinational setting. A total of 294 patients fro...

The socio-economic impact of robotic prosthetics: the Hannes hand case study.

Scientific reports
Social impact assessment has gained increasing attention in recent years, emphasizing the added value and social changes brought by project activities alongside the sustainability of social actions. This study evaluates the economic and social impact...

Automated segmentation of brain metastases in magnetic resonance imaging using deep learning in radiotherapy.

Scientific reports
Brain metastases (BMs) are the most common intracranial tumors and stereotactic radiotherapy improved the life quality of patient with BMs, while it requires more time and experience to delineate BMs precisely by oncologists. Deep Learning techniques...

Autonomous artificial intelligence prescribing a drug to prevent severe acute graft-versus-host disease in HLA-haploidentical transplants.

Nature communications
Autonomous artificial intelligence (AI) models for deciding treatment strategies are available but rarely applied prospectively in clinical settings. Here we present a prospective study of deploying daGOAT, an algorithm we have developed, as a condit...