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Dissecting Shared Genetic Architecture of Thoracic Aortic Aneurysm and Aortic Related Traits and Identifying SplA/Ryanodine Receptor Domain and SOCS Box Containing 1 Involved in Smooth Muscle Phenotype Switching and Cell Senescence Through Alternative Splicing.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Machine learning was employed to annotate images of the thoracic aorta, resulting in the identification of additional thoracic-related targets. However, genetic evaluation of the associations among thoracic aortic traits and their shared genes is lac...

A study on sex prediction by using machine algorithms with anthropometric measurements of the seventh cervical vertebra.

Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur
Prediction of sex is among important topics of forensic medicine and forensic anthropology. In studies conducted for sex prediction, pelvis and cranium bones are the most preferred bones. In cases when it is difficult to examine the pelvis and craniu...

Artificial intelligence-based flow cytometry for the diagnosis of B-cell chronic lymphoproliferative disorders.

Blood advances
Accurate diagnosis of B-cell chronic lymphoproliferative disorders (B-CLPDs) remains challenging due to overlapping phenotypes across subtypes. Machine learning (ML) offers promising tools to improve marker evaluation and refine flow cytometry analys...

An AI model classifies risks of early relapse post-CAR T-cell therapy in a multicenter real-world population with DLBCL.

Blood advances
Accumulating real-world (RW) evidence of axicabtagene ciloleucel (axi-cel) has demonstrated comparable performance to that of pivotal trials. However, ∼57% of patients eventually relapse, with most requiring additional therapies. Being able to identi...

Comparative reproductive biology, advances in reproductive health, and cultivating inclusion in the scientific community: highlights from the 2024 Annual Meeting of the Society for Reproductive Biology.

Reproduction, fertility, and development
In 2024, the reproductive biology research community in Australia and New Zealand reunited in Adelaide for the Society for Reproductive Biology (SRB) Annual Meeting. The conference showcased major advances made in key areas of reproductive biology, w...

[Impacts and implications of conversational artificial intelligence tools in hematology: a critical evaluation of performance and patient perception].

Annales de biologie clinique
Large Language Models (LLMs), such as ChatGPT, Gemini, and Copilot, are generating growing interest for their ability to produce accessible medical responses. In hematology, a discipline focused on the interpretation of complex test results, these to...

Artificial intelligence-enhanced electrocardiography to predict regurgitant valvular heart diseases: an international study.

European heart journal
BACKGROUND AND AIMS: Valvular heart disease (VHD) is a significant source of morbidity and mortality, though early intervention can improve outcomes. This study aims to develop artificial intelligence-enhanced electrocardiography (AI-ECG) models to d...

Plasma lipid levels predict chemotherapy response and survival in acute myeloid leukemia.

Blood
Acute myeloid leukemia (AML) is characterized by a low 5-year survival rate. Despite having many clinical metrics to assess patient prognosis, there remain opportunities to improve risk stratification. We hypothesized that an underexplored resource t...

Application of real-time artificial intelligence to cataract surgery.

The British journal of ophthalmology
BACKGROUND/AIMS: Artificial intelligence (AI) in Ophthalmology has yet to be applied to real-time cataract surgery. This work explores a new AI tool, developed for phacoemulsification, and evaluates its potential uses.First, our study aimed to demons...