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Metabolomic machine learning-based model predicts efficacy of chemoimmunotherapy for advanced lung squamous cell carcinoma.

Frontiers in immunology
BACKGROUND: Unlike lung adenocarcinoma, patients with advanced squamous carcinoma exhibit a low proportion of driver gene positivity, with fewer effective treatment strategies available. Chemoimmunotherapy has now become the standard first-line treat...

Identifying the Most Critical Predictors of Workplace Violence Experienced by Junior Nurses: An Interpretable Machine Learning Perspective.

Journal of nursing management
Workplace violence, defined as any disruptive behavior or threat to employees, seriously threatens junior nurses. Compared with senior nurses, junior nurses are more vulnerable to workplace violence due to inexperience, low professional recognition,...

Understanding patterns of loneliness in older long-term care users using natural language processing with free text case notes.

PloS one
Loneliness and social isolation are distressing for individuals and predictors of mortality, yet data on their impact on publicly funded long-term care is limited. Using recent advances in natural language processing (NLP), we analysed pseudonymised ...

Development and validation of machine learning models for early diagnosis and prognosis of lung adenocarcinoma using miRNA expression profiles.

Cancer biomarkers : section A of Disease markers
ObjectiveStudy aims to develop diagnostic and prognostic models for lung adenocarcinoma (LUAD) using Machine learning(ML)algorithms, aiming to enhance clinical decision-making accuracy.MethodsData from The Cancer Genome Atlas (TCGA) for LUAD patients...

Foundation Model for Predicting Prognosis and Adjuvant Therapy Benefit From Digital Pathology in GI Cancers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE: Artificial intelligence (AI) holds significant promise for improving cancer diagnosis and treatment. Here, we present a foundation AI model for prognosis prediction on the basis of standard hematoxylin and eosin-stained histopathology slides...

Optimizing bladder magnetic resonance imaging: accelerating scan time and improving image quality through deep learning.

Abdominal radiology (New York)
PURPOSE: To investigate the value of deep learning (DL) in T2-weighted imaging (T2) of the bladder regarding acquisition time (TA), image quality, and diagnostic confidence compared to standard T2-weighted turbo-spin-echo (TSE) imaging (T2).

Automated Whole-Liver Fat Quantification with Magnetic Resonance Imaging-Derived Proton Density Fat Fraction Map: A Prospective Study in Taiwan.

Gut and liver
BACKGROUND/AIMS: Magnetic resonance imaging (MRI) with a proton density fat fraction (PDFF) sequence is the most accurate, noninvasive method for assessing hepatic steatosis. However, manual measurement on the PDFF map is time-consuming. This study a...

Gene age gap estimate (GAGE) for major depressive disorder: A penalized biological age model using gene expression.

Neurobiology of aging
Recent associations between Major Depressive Disorder (MDD) and measures of premature aging suggest accelerated biological aging as a potential biomarker for MDD susceptibility or MDD as a risk factor for age-related diseases. Residuals or "gaps" bet...