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High-Throughput Deep Learning Detection of Mitral Regurgitation.

Circulation
BACKGROUND: Diagnosis of mitral regurgitation (MR) requires careful evaluation by echocardiography with Doppler imaging. This study presents the development and validation of a fully automated deep learning pipeline for identifying apical 4-chamber v...

Prediction of neurologic outcome after out-of-hospital cardiac arrest: An interpretable approach with machine learning.

Resuscitation
UNLABELLED: Out-of-hospital cardiac arrest (OHCA) is a critical condition with low survival rates. In patients with a return of spontaneous circulation, brain injury is a leading cause of death. In this study, we propose an interpretable machine lear...

Utilizing machine learning to integrate single-cell and bulk RNA sequencing data for constructing and validating a novel cell adhesion molecules related prognostic model in gastric cancer.

Computers in biology and medicine
BACKGROUND: Cell adhesion molecules (CAMs) play a vital role in cell-cell interactions, immune response modulation, and tumor cell migration. However, the unique role of CAMs in gastric cancer (GC) remains largely unexplored.

Capability of multimodal large language models to interpret pediatric radiological images.

Pediatric radiology
BACKGROUND: There is a dearth of artificial intelligence (AI) development and research dedicated to pediatric radiology. The newest iterations of large language models (LLMs) like ChatGPT can process image and video input in addition to text. They ar...

Assessment of EMR ML Mining Methods for Measuring Association between Metal Mixture and Mortality for Hypertension.

High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension
INTRODUCTION: There are limited data available regarding the connection between heavy metal exposure and mortality among hypertension patients.

Feedback control of heart rate during robotics-assisted tilt table exercise in patients after stroke: a clinical feasibility study.

Journal of neuroengineering and rehabilitation
BACKGROUND: Patients with neurological disorders including stroke use rehabilitation to improve cognitive abilities, to regain motor function and to reduce the risk of further complications. Robotics-assisted tilt table technology has been developed ...

Artificial intelligence reveals the predictions of hematological indexes in children with acute leukemia.

BMC cancer
Childhood leukemia is a prevalent form of pediatric cancer, with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) being the primary manifestations. Timely treatment has significantly enhanced survival rates for children with acute ...

Development and experimental validation of hypoxia-related gene signatures for osteosarcoma diagnosis and prognosis based on WGCNA and machine learning.

Scientific reports
Osteosarcoma (OS) is the most common primary malignant tumour of the bone with high mortality. Here, we comprehensively analysed the hypoxia signalling in OS and further constructed novel hypoxia-related gene signatures for OS prediction and prognosi...

Age prediction from 12-lead electrocardiograms using deep learning: a comparison of four models on a contemporary, freely available dataset.

Physiological measurement
The 12-lead electrocardiogram (ECG) is routine in clinical use and deep learning approaches have been shown to have the identify features not immediately apparent to human interpreters including age and sex. Several models have been published but no ...

Coagulation Risk Predicting in Anticoagulant-Free Continuous Renal Replacement Therapy.

Blood purification
INTRODUCTION: Continuous renal replacement therapy (CRRT) is a prolonged continuous extracorporeal blood purification therapy to replace impaired renal function. Typically, CRRT therapy requires routine anticoagulation, but for patients at risk of bl...