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Mesenchymal Stem Cells

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[rhPDGF-BB promotes migration of bone marrow stromal stem cells in diabetic rats].

Shanghai kou qiang yi xue = Shanghai journal of stomatology
PURPOSE: To evaluate the effect of different concentrations of rhPDGF-BB on bone marrow stromal stem cells(BMSCs) migration in diabetic rat, and related mechanisms of SDF-1 and its G-protein conjugated receptor regulation, provide a theoretical basis...

[Acupoint injection of BMSCs combined with Chinese herbs for capillary density in ischemic hind limb of diabetes mellitus rats].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion
OBJECTIVE: To observe the effect of acupoint injection of bone mesenchymal stem cells (BMSCs) combined with Chinese herbs of benefiting for activating blood circulation for capillary density and arterioles density in skeletal muscle in ischemic hind...

Cell mitosis event analysis in phase contrast microscopy images using deep learning.

Medical image analysis
In this paper, we solve the problem of mitosis event localization and its stage localization in time-lapse phase-contrast microscopy images. Our method contains three steps: first, we formulate a Low-Rank Matrix Recovery (LRMR) model to find salient ...

Evaluating adipocyte differentiation of bone marrow-derived mesenchymal stem cells by a deep learning method for automatic lipid droplet counting.

Computers in biology and medicine
Stem cells are a group of competent cells capable of self-renewal and differentiating into osteogenic, chondrogenic, and adipogenic lineages. These cells provide the possibility of successfully treating patients. During differentiation into adipose t...

Quantitative scoring of epithelial and mesenchymal qualities of cancer cells using machine learning and quantitative phase imaging.

Journal of biomedical optics
SIGNIFICANCE: We introduce an application of machine learning trained on optical phase features of epithelial and mesenchymal cells to grade cancer cells' morphologies, relevant to evaluation of cancer phenotype in screening assays and clinical biops...

Bioinspired Soft Microrobots with Precise Magneto-Collective Control for Microvascular Thrombolysis.

Advanced materials (Deerfield Beach, Fla.)
New-era soft microrobots for biomedical applications need to mimic the essential structures and collective functions of creatures from nature. Biocompatible interfaces, intelligent functionalities, and precise locomotion control in a collective manne...

Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.

PLoS computational biology
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's conditions would provide va...