AIMC Topic: Mice, Inbred BALB C
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Plasmonic MoO nanoparticles incorporated in Prussian blue frameworks exhibit highly efficient dual photothermal/photodynamic therapy.
Journal of materials chemistry. B
Feb 21, 2019
Development of near infrared (NIR) light-responsive nanomaterials for high performance multimodal phototherapy within a single nanoplatform is still challenging in technology and biomedicine. Herein, a new phototherapeutic nanoagent based on FDA-appr...
Neuronal survival of DRG neurons after neurite transection in vitro promotes by nerve growth factor and brain derived neurotrophic factor.
Cellular and molecular biology (Noisy-le-Grand, France)
Dec 31, 2018
Neurotrophic factors are growth factors that promote neuronal survival, regulate synaptic function and neurotransmitter release, and promote the plasticity and growth of axons in the peripheral and central nervous systems. This study focused on the r...
CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus.
Iranian journal of allergy, asthma, and immunology
Dec 3, 2018
Among many pneumococcal antigens, choline-binding proteins (CPBs) display a high immunogenicity in animal models. This study aims to determine the immunogenicity of CbpM, CbpG and CbpL proteins of Streptococcus pneumoniae in a mice model. The genes w...
Cell dynamic morphology classification using deep convolutional neural networks.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
May 15, 2018
Cell morphology is often used as a proxy measurement of cell status to understand cell physiology. Hence, interpretation of cell dynamic morphology is a meaningful task in biomedical research. Inspired by the recent success of deep learning, we here ...
Computational Analysis of Cell Dynamics in Videos with Hierarchical-Pooled Deep-Convolutional Features.
Journal of computational biology : a journal of computational molecular cell biology
Apr 25, 2018
Computational analysis of cellular appearance and its dynamics is used to investigate physiological properties of cells in biomedical research. In consideration of the great success of deep learning in video analysis, we first introduce two-stream co...
Antiproliferative and anti-apoptotic effect of astaxanthin in an oxygen-induced retinopathy mouse model.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
Apr 11, 2018
OBJECTIVE: To evaluate the impact of intravitreal (IV) and intraperitoneal (IP) astaxanthin (AST) injections on neovascular development (ND), retinal morphology, and apoptotic activity in a C57BL/6J mouse model with hyperoxia-induced retinopathy (HIR...
Design and synthesis of cell selective α/β-diastereomeric peptidomimetic with potent in vivo antibacterial activity against methicillin resistant S. Aureus.
Bioorganic chemistry
Dec 26, 2017
Design of therapeutically viable antimicrobial peptides with cell selectivity against microorganisms is an important step towards the development of new antimicrobial agents. Here, we report four de novo designed, short amphipathic sequences based on...
Humans
Anti-Bacterial Agents
Female
Animals
Microbial Sensitivity Tests
Acinetobacter baumannii
Hemolysis
Lipid Bilayers
Peptidomimetics
Phosphatidylglycerols
Stereoisomerism
Pseudomonas aeruginosa
Keratinocytes
Enterococcus faecalis
Phosphatidylcholines
Erythrocytes
Escherichia coli
Methicillin-Resistant Staphylococcus aureus
Mice, Inbred BALB C
Amino Acid Sequence
[In vitro Modulating Activity of aqueous extracts from American Plants on Chlorpyrifos-induced toxicity on Murine Splenocytes].
Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)
Dec 21, 2017
BACKGROUND: Chlorpyrifos is an highly toxic pesticide, which can induce immunotoxicity with deleterious effects on health worldwide. On the other hand, American plants can provide derivatives with protective and immunostimulating activity. Thus, plan...
Salinomycin-loaded lipid-polymer nanoparticles with anti-CD20 aptamers selectively suppress human CD20+ melanoma stem cells.
Acta pharmacologica Sinica
Dec 14, 2017
Melanoma is the deadliest type of skin cancer. CD20+ melanoma stem cells (CSCs) are pivotal for metastasis and initiation of melanoma. Therefore, selective elimination of CD20+ melanoma CSCs represents an effective treatment to eradicate melanoma. Sa...
Lycopene-rich extract from red guava (Psidium guajava L.) displays cytotoxic effect against human breast adenocarcinoma cell line MCF-7 via an apoptotic-like pathway.
Food research international (Ottawa, Ont.)
Oct 27, 2017
This study investigated a lycopene-rich extract from red guava (LEG) for its chemical composition using spectrophotometry, mass spectrometry, attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR), and computational studies. ...
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