AIMC Topic: Microelectrodes

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Real-Time Monitoring and Analysis of Zebrafish Electrocardiogram with Anomaly Detection.

Sensors (Basel, Switzerland) Dec 28, 2017
Heart disease is the leading cause of mortality in the U.S. with approximately 610,000 people dying every year. Effective therapies for many cardiac diseases are lacking, largely due to an incomplete understanding of their genetic basis and underlyin...
Microelectrodes Heart Animals Zebrafish Signal-To-Noise Ratio Electrocardiography
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A multivariate extension of mutual information for growing neural networks.

Neural networks : the official journal of the International Neural Network Society Jul 24, 2017
Recordings of neural network activity in vitro are increasingly being used to assess the development of neural network activity and the effects of drugs, chemicals and disease states on neural network function. The high-content nature of the data der...
Neural Networks, Computer Action Potentials Microelectrodes Patch-Clamp Techniques Neurons Microarray Analysis
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Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform.

ACS synthetic biology Jun 7, 2017
Electrowetting-on-dielectric (EWD) digital microfluidic laboratory-on-a-chip platforms demonstrate excellent performance in automating labor-intensive protocols. When coupled with an on-chip electroporation capability, these systems hold promise for ...
Signal Processing, Computer-Assisted Transfection Lab-On-A-Chip Devices Escherichia coli Robotics Equipment Design Transformation, Bacterial Microelectrodes Equipment Failure Analysis Electroporation
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A robot for high yield electrophysiology and morphology of single neurons in vivo.

Nature communications Jun 1, 2017
Single-cell characterization and perturbation of neurons provides knowledge critical to addressing fundamental neuroscience questions including the structure-function relationship and neuronal cell-type classification. Here we report a robot for effi...
Equipment Design Neurons Models, Animal Microelectrodes Electroporation Electrophysiological Phenomena Mice Mice, Inbred C57BL Robotics Male Single-Cell Analysis Software Brain Female Animals
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Sparse and Specific Coding during Information Transmission between Co-cultured Dentate Gyrus and CA3 Hippocampal Networks.

Frontiers in neural circuits Mar 6, 2017
To better understand encoding and decoding of stimulus information in two specific hippocampal sub-regions, we isolated and co-cultured rat primary dentate gyrus (DG) and CA3 neurons within a two-chamber device with axonal connectivity via micro-tunn...
Machine Learning Evoked Potentials Nerve Net Rats CA3 Region, Hippocampal Dentate Gyrus Cells, Cultured Models, Neurological Microelectrodes Animals Neurons
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Stop! border ahead: Automatic detection of subthalamic exit during deep brain stimulation surgery.

Movement disorders : official journal of the Movement Disorder Society Oct 6, 2016
BACKGROUND: Microelectrode recordings along preplanned trajectories are often used for accurate definition of the subthalamic nucleus (STN) borders during deep brain stimulation (DBS) surgery for Parkinson's disease. Usually, the demarcation of the S...
Electrodes, Implanted Electrophysiological Phenomena Subthalamic Nucleus Markov Chains Substantia Nigra Signal Processing, Computer-Assisted Microelectrodes Humans Deep Brain Stimulation Middle Aged Female Support Vector Machine Aged Parkinson Disease Male
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Unsupervised neural spike sorting for high-density microelectrode arrays with convolutive independent component analysis.

Journal of neuroscience methods Jun 15, 2016
BACKGROUND: Unsupervised identification of action potentials in multi-channel extracellular recordings, in particular from high-density microelectrode arrays with thousands of sensors, is an unresolved problem. While independent component analysis (I...
Artifacts Computer Simulation Microelectrodes Animals Rabbits Models, Theoretical Retina Action Potentials Neurons Unsupervised Machine Learning
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Virtual white matter: a novel system for cross-dish neural interaction and modulation.

Journal of neural engineering May 14, 2025
. Biological neural networks (BNNs) are characterized by complex interregional connectivity, allowing for seamless communication between different brain regions.models traditionally consist of single-dish neural cultures that cannot recapitulate the ...
Neural Networks, Computer Cells, Cultured Animals Humans Nerve Net Microelectrodes Rats Electric Stimulation Neurons White Matter
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Information sparseness in cortical microelectrode channels while decoding movement direction using an artificial neural network.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jul 1, 2022
Implanted microelectrode arrays can directly pick up electrode signals from the primary motor cortex (M1) during movement, and brain-machine interfaces (BMIs) can decode these signals to predict the directions of contemporaneous movements. However, i...
Movement Upper Extremity Neural Networks, Computer Brain-Computer Interfaces Microelectrodes
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A Multi-Modular System for the Visualization and Classification of MER Data During Neurostimulation Procedures.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Nov 1, 2021
This paper proposes an interactive analysis and visualization tool for the accuracy improvement of electrode placement during neurostimulation therapy surgery. During the procedure, the presented system assists the surgeon in the crucial tissue type ...
Machine Learning Magnetic Resonance Imaging Microelectrodes Neural Networks, Computer
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