This paper describes a nanoliter droplet array-based single-cell reverse transcription quantitative PCR (RT-qPCR) assay method for quantifying gene expression in individual cells. By sequentially printing nanoliter-scale droplets on microchip using a...
Identification of microRNAs (miRNAs) is an important step toward understanding post-transcriptional gene regulation and miRNA-related pathology. Difficulties in identifying miRNAs through experimental techniques combined with the huge amount of data ...
Since Ambros' discovery of small non-protein coding RNAs in the early 1990s, the past two decades have seen an upsurge in the number of reports of predicted microRNAs (miR), which have been implicated in various functions. The correlation of miRs wit...
BACKGROUND: microRNAs (miRNAs) play a vital role in development, oncogenesis, and apoptosis by binding to mRNAs to regulate the posttranscriptional level of coding genes in mammals, plants, and insects. Recent studies have demonstrated that the expre...
Genetics and molecular research : GMR
Jan 15, 2015
Imbalances typically exist in bioinformatics and are also common in other areas. A drawback of traditional machine learning methods is the relatively little attention given to small sample classification. Thus, we developed imDC, which uses an ensemb...
Epstein-Barr Virus (EBV) is the first tumor virus discovered in humans, which is closely related to the occurrence of a variety of malignant tumors, especially Nasopharyngeal Carcinoma (NPC). Epstein-Barr Virus (EBV)-associated NPC accounts for appro...
Dysregulated microRNAs (miRNAs) play a significant role in cancer development and metastasis. In literature, miRNAs have been used for the survival prediction of different types of cancers using AI. Although AI is useful for diagnosis and prognosis p...
MicroRNAs (miRNAs) are evolutionarily conserved small regulatory elements that are ubiquitous in cells and are found to be abnormally expressed during the onset and progression of several human diseases. miRNAs are increasingly recognized as potentia...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Jun 30, 2025
Heterotopic ossification (HO) is a pathological process where bone forms in extraskeletal tissues, often occurring as a complication of tissue repair following injury. This condition can lead to movement limitations, pain, and functional impairment. ...
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