RATIONALE AND OBJECTIVES: This study aims to develop and validate a novel two-step deep learning framework for the automated detection, segmentation, and classification of bone metastases in SPECT/CT imaging, accurately distinguishing malignant from ...
OBJECTIVE: To develop a dynamic contrast-enhanced ultrasound (CEUS)-based method for segmenting tumor perfusion subregions, quantifying tumor heterogeneity, and constructing models for distinguishing benign from malignant breast tumors.
Cardiovascular-kidney-metabolic syndrome (CKM) and its association with exposure to emerging pollutants, particularly perfluoroalkyl and polyfluoroalkyl substances (PFAS), present significant challenges for environmental public health and risk predic...
BACKGROUND AND OBJECTIVES: Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the CNS characterized by a heterogeneous disease trajectory, highlighting the need for biomarkers to predict disease activity. Current disease-monitorin...
BACKGROUND: Recently, western countries have built evidence on mammographic artificial Intelligence-computer-aided diagnosis (AI-CADx) systems; however, their effectiveness has not yet been sufficiently validated in Japanese women. In this study, we ...
BACKGROUND: Functional magnetic resonance imaging (fMRI) is a powerful tool for non-invasive evaluation of micro-changes in the kidneys. This study aims to develop classification and prognostic models based on multi-modal data.
OBJECTIVE: To develop a multimodal model to predict chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM), given the limited research on this integrative approach.
Ecotoxicology and environmental safety
Sep 1, 2025
3-Monochloropropane-1,2-diol (3-MCPD) and glycidol along with their esters are commonly found in chemical production, wastewater treatment, food processing, and exhibit toxicity. Accurate exposure assessment is essential for evaluating the environmen...
AIMS: Obesity is associated with functional alterations in the brain. Although spatial organisation changes in the brains of individuals with obesity have been widely studied, the temporal dynamics in their brains remain poorly understood. Therefore,...
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