AIMC Topic: Middle Aged

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Deep learning detected histological differences between invasive and non-invasive areas of early esophageal cancer.

Cancer science
The depth of invasion plays a critical role in predicting the prognosis of early esophageal cancer, but the reasons behind invasion and the changes occurring in invasive areas are still not well understood. This study aimed to explore the morphologic...

Detection of late gadolinium enhancement in patients with hypertrophic cardiomyopathy using machine learning.

International journal of cardiology
BACKGROUND: Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) in hypertrophic cardiomyopathy (HCM) typically represents myocardial fibrosis and may lead to fatal ventricular arrhythmias. However, CMR is resource-intensive and some...

Evaluation of a machine learning-based metabolic marker for coronary artery disease in the UK Biobank.

Atherosclerosis
BACKGROUND AND AIMS: An in silico quantitative score of coronary artery disease (ISCAD), built using machine learning and clinical data from electronic health records, has been shown to result in gradations of risk of subclinical atherosclerosis, cor...

Prediction of new-onset atrial fibrillation in patients with hypertrophic cardiomyopathy using machine learning.

European journal of heart failure
AIMS: Atrial fibrillation (AF) is the most common sustained arrhythmia among patients with hypertrophic cardiomyopathy (HCM), leading to increased symptom burden and risk of thromboembolism. The HCM-AF score was developed to predict new-onset AF in p...

Radiomics and deep learning features of pericoronary adipose tissue on non-contrast computerized tomography for predicting non-calcified plaques.

Journal of X-ray science and technology
BACKGROUND: Inflammation of coronary arterial plaque is considered a key factor in the development of coronary heart disease. Early the plaque detection and timely treatment of the atherosclerosis could effectively reduce the risk of cardiovascular e...

Recognizing SARS-CoV-2 infection of nasopharyngeal tissue at the single-cell level by machine learning method.

Molecular immunology
SARS-CoV-2 has posed serious global health challenges not only because of the high degree of virus transmissibility but also due to its severe effects on the respiratory system, such as inducing changes in multiple organs through the ACE2 receptor. T...

Knowledge is not all you need for comfort in use of AI in healthcare.

Public health
OBJECTIVES: The adoption of artificial intelligence (AI) in healthcare is rapidly expanding, transforming areas such as diagnostics, drug discovery, and patient monitoring. Despite these advances, public perceptions of AI in healthcare, particularly ...

Metabolomic age (MileAge) predicts health and life span: A comparison of multiple machine learning algorithms.

Science advances
Biological aging clocks produce age estimates that can track with age-related health outcomes. This study aimed to benchmark machine learning algorithms, including regularized regression, kernel-based methods, and ensembles, for developing metabolomi...