AIMC Topic: Middle Aged
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Associations between weight gain, integrase inhibitors antiretroviral agents, and gut microbiome in people living with HIV: a cross-sectional study.
Scientific reports
Jul 2, 2025
Dolutegravir and bictegravir are second-generation HIV integrase strand transfer inhibitors (INSTIs) that were previously associated with abnormal weight gain. This monocentric cross-sectional study investigates associations between weight gain durin...
Automated grading of rectocele with an MRI radiomics model.
Scientific reports
Jul 2, 2025
To develop an automated grading model for rectocele (RC) based on radiomics and evaluate its efficacy. This study retrospectively analyzed a total of 9,392 magnetic resonance imaging (MRI) images obtained from 222 patients who underwent dynamic magne...
AI-driven analysis by identifying risk factors of VL relapse in HIV co-infected patients.
Scientific reports
Jul 1, 2025
Visceral Leishmaniasis (VL), also known as Kala-Azar, poses a significant global public health challenge and is a neglected disease, with relapses and treatment failures leading to increased morbidity and mortality. This study introduces an explainab...
Deep learning for occupation recognition and knowledge discovery in rheumatology clinical notes.
Scientific reports
Jul 1, 2025
Occupational data is a crucial social determinant of health, influencing diagnostic accuracy, treatment strategies, and policy-making in healthcare. However, its inclusion in electronic health records (EHR) is often relegated to unstructured fields. ...
Activated cancer-associated fibroblasts correlate with poor survival and decreased lymphocyte infiltration in infiltrative type distal cholangiocarcinoma.
Scientific reports
Jul 1, 2025
Cancer-associated fibroblasts promote tumor progression through growth facilitation, invasion, and immune evasion. This study investigated the impact of activated cancer-associated fibroblasts (aCAFs) on survival outcomes, immune response, and molecu...
Comparison of AI chatbot predicted and realworld survival outcomes in hepatocellular carcinoma.
Scientific reports
Jul 1, 2025
This study compares survival predictions made by an artificial intelligence (AI) based chatbot with real-world data in hepatocellular carcinoma (HCC) patients. It aims to evaluate the reliability and accuracy of AI technologies in HCC prognosis. A re...
Evaluation of MRI-based synthetic CT for lumbar degenerative disease: a comparison with CT.
Scientific reports
Jul 1, 2025
Patients with lumbar degenerative disease typically undergo preoperative MRI combined with CT scans, but this approach introduces additional ionizing radiation and examination costs. To compare the effectiveness of MRI-based synthetic CT (sCT) in dis...
Metabolomic biomarkers could be molecular clocks in timing stroke onset.
Scientific reports
Jul 1, 2025
The preferred treatment for acute ischaemic stroke (AIS) is intravenous thrombolysis (IVT) administered within 4.5 hours (h) of symptom onset. This study aimed to identify metabolomic biomarkers for distinguishing AIS patients within 4.5 h of symptom...
Beyond accuracy: a framework for evaluating algorithmic bias and performance, applied to automated sleep scoring.
Scientific reports
Jul 1, 2025
Recent advancements in artificial intelligence (AI) have significantly improved sleep-scoring algorithms, bringing their performance close to the theoretical limit of approximately 80%, which aligns with inter-scorer agreement levels. While this sugg...
AI-based CT assessment of 3117 vertebrae reveals significant sex-specific vertebral height differences.
Scientific reports
Jul 1, 2025
Predicting vertebral height is complex due to individual factors. AI-based medical imaging analysis offers new opportunities for vertebral assessment. Thereby, these novel methods may contribute to sex-adapted nomograms and vertebral height predictio...
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