AIMC Topic: Middle Aged

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Artificial Intelligence for Predicting HER2 Status of Gastric Cancer Based on Whole-Slide Histopathology Images: A Retrospective Multicenter Study.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Human epidermal growth factor receptor 2 (HER2) positive gastric cancer (GC) shows a robust response to the combined therapy based HER2-targeted therapy. The application of these therapies is highly dependent on the evaluation of tumor HER2 status. H...

Patient- and clinician-based evaluation of large language models for patient education in prostate cancer radiotherapy.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
BACKGROUND: This study aims to evaluate the capabilities and limitations of large language models (LLMs) for providing patient education for men undergoing radiotherapy for localized prostate cancer, incorporating assessments from both clinicians and...

Automated classification of coronary LEsions fRom coronary computed Tomography angiography scans with an updated deep learning model: ALERT study.

European radiology
OBJECTIVES: The use of deep learning models for quantitative measurements on coronary computed tomography angiography (CCTA) may reduce inter-reader variability and increase efficiency in clinical reporting. This study aimed to investigate the diagno...

Development and routine implementation of deep learning algorithm for automatic brain metastases segmentation on MRI for RANO-BM criteria follow-up.

NeuroImage
RATIONALE AND OBJECTIVES: The RANO-BM criteria, which employ a one-dimensional measurement of the largest diameter, are imperfect due to the fact that the lesion volume is neither isotropic nor homogeneous. Furthermore, this approach is inherently ti...

Machine learning in public health informatics: Evidence that complex sampling structures may not be needed for prediction models with imbalanced outcomes.

Annals of epidemiology
PURPOSE: The objective of this study is to investigate the predictive ability of machine learning models for imbalanced outcomes from national survey data without the use of sampling weights.

Predicting cognitive decline from neuropsychiatric symptoms and Alzheimer's disease biomarkers: A machine learning approach to a population-based data.

Journal of Alzheimer's disease : JAD
BACKGROUND: The aim of this study was to examine the potential added value of including neuropsychiatric symptoms (NPS) in machine learning (ML) models, along with demographic features and Alzheimer's disease (AD) biomarkers, to predict decline or no...

Machine learning-based prediction model integrating ultrasound scores and clinical features for the progression to rheumatoid arthritis in patients with undifferentiated arthritis.

Clinical rheumatology
OBJECTIVES: Predicting rheumatoid arthritis (RA) progression in undifferentiated arthritis (UA) patients remains a challenge. Traditional approaches combining clinical assessments and ultrasonography (US) often lack accuracy due to the complex intera...

A novel machine learning-based immune prognostic signature for improving clinical outcomes and guiding therapy in colorectal cancer: an integrated bioinformatics and experimental study.

BMC cancer
Immune cells are pivotal components in the tumor microenvironment (TME), which can interact with tumor cells and significantly influence cancer progression and therapeutic outcomes. Therefore, classifying cancer patients based on the status of immune...

Predictive models and determinants of mortality among T2DM patients in a tertiary hospital in Ghana, how do machine learning techniques perform?

BMC endocrine disorders
BACKGROUND: The increasing prevalence of type 2 diabetes mellitus (T2DM) in lower and middle - income countries call for preventive public health interventions. Studies from Africa including those from Ghana, consistently reveal high T2DM-related mor...

Machine learning in the prediction of human wellbeing.

Scientific reports
Subjective wellbeing data are increasingly used across the social sciences. Yet, despite the widespread use of such data, the predictive power of approaches commonly used to model wellbeing is only limited. In response, we here use tree-based Machine...