AIMC Topic: Middle Aged

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Association between atherogenic index of plasma and sepsis in critically ill patients with ischemic stroke: a retrospective cohort study using propensity score and machine learning approaches.

Lipids in health and disease
BACKGROUND: Sepsis is a severe and frequent complication among ischemic stroke patients during hospitalization. The atherogenic index of plasma (AIP), as metabolism-related markers, are closely linked to inflammation. However, their relationship with...

Multi-channel deep learning radiomics model based on contrast-enhanced CT for predicting postoperative prognosis in laryngeal carcinoma.

BMC cancer
BACKGROUND: Accurate prediction of prognosis and risk stratification in patients with laryngeal cancer can inform appropriate treatment decision-making. This study aims to develop a multi-channel deep learning radiomics model based on contrast-enhanc...

Morphometric similarity network-based graph convolutional networks for schizophrenia classification.

Scientific reports
Schizophrenia is a complex neuropsychiatric disorder characterized by significant heterogeneity, posing a challenge for accurate classification using neuroimaging data. Graph convolutional networks (GCNs) have emerged as a promising approach for leve...

Using magnetic resonance imaging-based subregional texture analysis models to classify knee osteoarthritis severity by compartment.

Scientific reports
We evaluated the effectiveness of magnetic resonance imaging (MRI)-based subregional texture analysis (TA) models for classifying knee osteoarthritis (OA) severity grades by compartment. We identified 122 MR images of 121 patients with knee OA (mild-...

Modelling of immune infiltration in prostate cancer treated with HDR-brachytherapy using Raman spectroscopy and machine learning.

Scientific reports
Prostate cancer is characterized by an immunosuppressive tumour environment. This work combines Raman spectroscopy with group-and-bases-restricted non-negative matrix factorization (GBR-NMF) and machine learning to assemble models of immune cell dens...

Development and validation of a predictive model for diabetic peripheral neuropathy with type 2 diabetes mellitus in Xinjiang, China.

Scientific reports
This study aims to identify risk factors associated with diabetic peripheral neuropathy (DPN) in patients with type 2 diabetesmellitus (T2DM) and to develop a predictive model to support clinical decision-making. A total of 1,001 patients with T2DM w...

Convolutional neural network based system for fully automatic FLAIR MRI segmentation in multiple sclerosis diagnosis.

Scientific reports
This study presents an automated system using Convolutional Neural Networks (CNNs) for segmenting FLAIR Magnetic Resonance Imaging (MRI) images to aid in the diagnosis of Multiple Sclerosis (MS). The dataset included 103 patients from Imam Khomeini H...

Clinical Information Extraction From Notes of Veterans With Lymphoid Malignancies: Natural Language Processing Study.

JMIR medical informatics
BACKGROUND: Clinical natural language processing (cNLP) techniques are commonly developed and used to extract information from clinical notes to facilitate clinical decision-making and research. However, they are less established for rare diseases su...

A Machine Learning-Based Scoring System to Identify High Immunoactivity Microsatellite Stability Tumors by Quantifying Similarity to Microsatellite Instability-High Tumors in Colorectal Cancers: Development and Quantitative Study.

JMIR formative research
BACKGROUND: Microsatellite stability (MSS) colorectal cancers (CRCs) have a limited response to immune checkpoint inhibitors (ICIs) compared to microsatellite instability-high (MSI-H) CRCs. Nevertheless, previous studies have shown that some MSS CRCs...

Retinal microvascular differences between multiple sclerosis and neuromyelitis optica spectrum disorder: a cross-sectional study with diagnostic modeling.

Journal of neurology
BACKGROUND AND OBJECTIVES: Retinal alterations in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) remain unclear, especially the specific patterns and extent of microvascular change. This study aimed to compare these altera...