AIMC Topic: Middle Aged

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Relative importance of key life domains in explaining life satisfaction among older adults.

Journal of psychosomatic research
OBJECTIVE: Life satisfaction is a key element contributing to successful aging. Limited empirical studies have specifically explored the nature of the relationship between domain-specific satisfaction and global life satisfaction among older adults. ...

Comprehensive predictive modeling in subarachnoid hemorrhage: integrating radiomics and clinical variables.

Neurosurgical review
Subarachnoid hemorrhage (SAH) is a severe condition with high morbidity and long-term neurological consequences. Radiomics, by extracting quantitative features from Computed Tomograhpy (CT) scans, may reveal imaging biomarkers predictive of outcomes....

Individual muscle strengths in rehabilitation outcomes of distal radius fracture.

Journal of neuroengineering and rehabilitation
BACKGROUND: Distal radius fractures (DRFs) are common fracture types and elderly patients often struggle to achieve functional recovery, which could be overcome by precise rehabilitation. This study aims to develop an innovative approach for acquirin...

Deep learning classification of drug-related problems from pharmaceutical interventions issued by hospital clinical pharmacists during medication prescription review: a large-scale descriptive retrospective study in a French university hospital.

European journal of hospital pharmacy : science and practice
OBJECTIVES: Pharmaceutical interventions are proposals made by hospital clinical pharmacists to address sub-optimal uses of medications during prescription review. Pharmaceutical interventions include the identification of drug-related problems, thei...

Patient acceptability of CITOBOT for cervical cancer screening: A mixed-method study.

PloS one
This study assessed the acceptability of CITOBOT, a device for early cervical cancer screening in a real-world pilot setting as part of a translational research project aimed at designing and clinically validating a portable, cost-effective device su...

Exploring the association between volatile organic compound exposure and chronic kidney disease: evidence from explainable machine learning methods.

Renal failure
BACKGROUND: Chronic Kidney Disease (CKD) affects approximately 697.5 million people worldwide. Volatile organic compounds (VOCs) are emerging as potential risk factors, but their complex relationships with CKD may be underestimated by traditional lin...

Sleep disturbances and PTSD: identifying baseline predictors of insomnia response in an intensive treatment programme.

European journal of psychotraumatology
This study examined whether baseline demographic and clinical variables could predict clinically significant reductions in insomnia symptoms among veterans receiving a 2-week Cognitive Processing Therapy (CPT)-based intensive PTSD treatment programm...

Biomarker risk stratification with capsule sponge in the surveillance of Barrett's oesophagus: prospective evaluation of UK real-world implementation.

Lancet (London, England)
BACKGROUND: Endoscopic surveillance is the clinical standard for Barrett's oesophagus, but its effectiveness is inconsistent. We have developed a test comprising a pan-oesophageal cell collection device coupled with biomarkers to stratify patients in...

[Incidental pulmonary nodules on CT imaging: what to do?].

Nederlands tijdschrift voor geneeskunde
Incidental pulmonary nodules are very frequently found on CT imaging and may represent (early stage) lung cancers without any signs or symptoms. These incidental findings can be solid lesions or ground glass lesions that may be solitary or multiple. ...

Harnessing the machine learning and nomogram models: elevating prognostication in nonmetastatic gastric cancer with "double invasion" for personalized patient care.

European journal of medical research
OBJECTIVE: To develop and validate a machine learning framework combined with a nomogram for predicting recurrence after radical gastrectomy in patients with vascular and neural invasion.