AIMC Topic: Myocardial Infarction
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Clinical application of high-sensitivity cardiac troponin T test in acute myocardial infarction diagnosis.
Genetics and molecular research : GMR
Dec 22, 2015
The aim of this study was to investigate the clinical application of a high-sensitivity cardiac troponin T (hs-cTnT) test in the diagnosis of acute myocardial infarction (AMI). Serum levels of hs-cTnT and cardiac troponin I (cTnI) were detected in 24...
Edoxaban vs warfarin in patients with nonvalvular atrial fibrillation in the US Food and Drug Administration approval population: An analysis from the Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48 (ENGAGE AF-TIMI 48) trial.
American heart journal
Dec 1, 2015
BACKGROUND: Edoxaban is a specific anti-Xa inhibitor that, in comparison to warfarin, has been found to be noninferior for the prevention of stroke or systemic embolism (SSE) and to reduce bleeding significantly in patients with nonvalvular atrial fi...
Factor Xa
Factor Xa Inhibitors
Drug Approval
Atrial Fibrillation
United States Food and Drug Administration
Thiazoles
Thrombolytic Therapy
Anticoagulants
Blood Coagulation
Double-Blind Method
Warfarin
Stroke
Myocardial Infarction
Male
United States
Dose-Response Relationship, Drug
Pyridines
Humans
Female
Aged
Aggressive hydraTion in patients with ST-Elevation Myocardial infarction undergoing Primary percutaneous coronary intervention to prevenT contrast-induced nephropathy (ATTEMPT): Study design and protocol for the randomized, controlled trial, the ATTEMPT, RESCIND 1 (First study for REduction of contraSt-induCed nephropathy followINg carDiac catheterization) trial.
American heart journal
Oct 20, 2015
Adequate hydration is recommended for acute ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) to prevent contrast-induced nephropathy (CIN). However, the optimal hydration regimen has not ...
Systems analysis of gene ontology and biological pathways involved in post-myocardial infarction responses.
BMC genomics
Jun 11, 2015
BACKGROUND: Pathway analysis has been widely used to gain insight into essential mechanisms of the response to myocardial infarction (MI). Currently, there exist multiple pathway databases that organize molecular datasets and manually curate pathway ...
Computer-aided diagnosis of Myocardial Infarction using ultrasound images with DWT, GLCM and HOS methods: A comparative study.
Computers in biology and medicine
Apr 10, 2015
Myocardial Infarction (MI) or acute MI (AMI) is one of the leading causes of death worldwide. Precise and timely identification of MI and extent of muscle damage helps in early treatment and reduction in the time taken for further tests. MI diagnosis...
Classifier calibration using splined empirical probabilities in clinical risk prediction.
Health care management science
Feb 21, 2014
The aims of supervised machine learning (ML) applications fall into three broad categories: classification, ranking, and calibration/probability estimation. Many ML methods and evaluation techniques relate to the first two. Nevertheless, there are ma...
Myocardial Infarction Detection using Variational Mode Decomposition with Fuzzy Weight Particle Swarm Optimization and Depthwise Separable Convolutional Network.
Computers in biology and medicine
Jul 1, 2025
The challenge of precisely recognizing myocardial infarction (MI) from electrocardiographic (ECG) readings stems from the complex nature of these signals.ECG data exhibit both nonlinear and non-stationary properties, making interpretation difficult. ...
Identification and analysis of diagnostic markers related to lactate metabolism in myocardial infarction.
Pathology, research and practice
Jul 1, 2025
Lactate metabolism is implicated in myocardial infarction (MI), yet the underlying mechanisms are not fully understood. Identifying lactate metabolism-related genes (LMRGs) could uncover new diagnostic and therapeutic targets for MI. We conducted a b...
Error correcting 2D-3D cascaded network for myocardial infarct scar segmentation on late gadolinium enhancement cardiac magnetic resonance images.
Medical image analysis
Jul 1, 2025
Late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) imaging is considered the in vivo reference standard for assessing infarct size (IS) and microvascular obstruction (MVO) in ST-elevation myocardial infarction (STEMI) patients. Howeve...
Re-engineering the clinical approach to suspected cardiac chest pain assessment in the emergency department by expediting research evidence to practice using artificial intelligence. (RAPIDx AI)-a cluster randomized study design.
American heart journal
Jul 1, 2025
BACKGROUND: Clinical work-up for suspected cardiac chest pain is resource intensive. Despite expectations, high-sensitivity cardiac troponin assays have not made decision making easier. The impact of recently validated rapid triage protocols includin...
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